1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid CAS 916591-87-2
| CAS No. | 916591-87-2 |
| Molecular Formula | C15H12F2N2O2 |
| Molecular Weight | 290.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid (C15H12F2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid (CAS 916591-87-2), a certified reference material (molecular formula C15H12F2N2O2, MW 290.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H12F2N2O2 |
| Molecular Weight | 290.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluorophenyl Standards
- 898759-63-2 (2,4-Difluorophenyl)[3-(1,3-dioxolan-2-yl)phenyl]methanone DTXSID50645086 (CAS 898759-63-2)
- 3-(2,4-Difluorophenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 19062-31-8)
- 6-(2,5-Difluorophenyl)-3-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 953908-56-0)
- 1,2-Bis(2,4-difluorophenyl)disulfane (CAS 876372-94-0)
- 1,2-Bis(3,4-difluorophenyl)disulfane (CAS 60811-25-8)
- 1-((2,6-Difluorophenyl)sulfonyl)-2,6-dimethylpiperidine (CAS 670272-11-4)
- 1-((2,6-Difluorophenyl)sulfonyl)-3,5-dimethylpiperidine (CAS 670272-07-8)
- 1-(3,5-Difluorophenyl)-2,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 1022324-58-8)
Recommended Standards
- (E)-2-((benzyloxy)imino)-N-(2,4-difluorophenyl)acetamide (CAS 866043-49-4)
- 2-(4-(Difluoromethoxy)phenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 453525-58-1)
- (4S,7R)-1-(2,4-Difluorophenyl)-4,5,6,7-tetrahydro-1H-4,7-methanoindazole-3-carboxylic acid (CAS 916591-88-3)
- 2,4-Difluoro-4-(1,3-dioxolan-2-yl)benzophenone (CAS 898760-76-4)
- 2-(6-Bromo-5-fluoro-1H-indol-3-yl)acetic acid (CAS 1227563-84-9)
- 5-Isobenzofurancarboxylic acid, 1,3-dihydro-1,3-dioxo-, polymer with 1,1'-methylenebis[4-isocyanatobenzene] (CAS 25053-57-0)
- 8-(5-Nitropyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane (CAS 877790-46-0)
- N-(3-Amino-4-fluorophenyl)-3-methoxybenzamide (CAS 926240-93-9)
- 1-(2-Ethoxy-6-hydroxyphenyl)ethan-1-one (CAS 2750-25-6)
- 5-(3-Chlorophenoxymethyl)furan-2-carbaldehyde (CAS 438220-92-9)
- 4-(Oxolan-3-yloxy)benzoic acid (CAS 1343204-85-2)
- 2,2,2-Trifluoroethyl n-(3-fluorophenyl)carbamate (CAS 200876-84-2)
- N-(1-(5-methyl-1H-pyrazol-3-yl)propan-2-yl)thietan-3-amine (CAS 1933548-26-5)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
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