Etizolam Impurity 7 CAS 91663-72-8
| CAS No. | 91663-72-8 |
| Molecular Formula | C14H9ClN4S |
| Molecular Weight | 300.77 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Etizolam Impurity 7 (CAS 91663-72-8, C14H9ClN4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Etizolam Impurity 7 (C14H9ClN4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 300.77 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Etizolam Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H9ClN4S |
| Molecular Weight | 300.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Etizolam Standards
- Etizolam Impurity 15 (CAS 51687-58-2)
- Etizolam Impurity 12 (CAS 67727-22-4)
- Etizolam Impurity 20 (CAS 50508-61-7)
- Etizolam Impurity 8 (CAS 54123-29-4)
- Etizolam Impurity 14 (CAS 40054-57-7)
- Etizolam Impurity 27 (CAS CATO-C4X-350927)
- Etizolam Impurity 4 (CAS 110753-14-5)
- Etizolam Impurity 31 (CAS CATO-C4X-350931)
Recommended Standards
- 2-(5-Chlorothiophen-2-yl)imidazo[2,1-a]phthalazin-6-amine (CAS 565168-88-9)
- Methyl 4-chloro-3-hydroxy-5-(phenylthio)thiophene-2-carboxylate (CAS 104386-58-5)
- N-Nitroso Nerandomilast impurity 12 (CAS CATO-C4X-347312)
- N-(2-Chlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-12-1)
- Ilaprazole impurity 189 (CAS CATO-C4X-1130189)
- Lidocaine Impurity 73 (CAS CATO-C4X-167973)
- Tandospirone impurity 19 (CAS 99095-09-7)
- 3-(2-Ethoxyethoxy)-5-methoxythiophene-2-carboxylic acid (CAS 1707581-43-8)
- 5-Fluoro-1,3-dihydroisobenzofuran (CAS 57584-70-0)
- 2,2,2-trifluoroethyl N-(2-chloropyridin-3-yl)carbamate (CAS 1354963-28-2)
- 3-(difluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 1339647-15-2)
- 1-(Isopropyl(methyl)amino)-3-(oxetan-3-ylthio)propan-2-ol (CAS 1862485-38-8)
- [4-(Benzyloxy)phenyl]methanethiol (CAS 80192-91-2)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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