Etizolam Impurity 12 CAS 67727-22-4
| CAS No. | 67727-22-4 |
| Molecular Formula | C13H9ClN2S2 |
| Molecular Weight | 292.81 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H9ClN2S2, Etizolam Impurity 12 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 292.81 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Etizolam Impurity 12 (CAS 67727-22-4), a pharmacopoeial impurity reference standard (molecular formula C13H9ClN2S2, MW 292.81 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H9ClN2S2 |
| Molecular Weight | 292.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Etizolam Standards
- Etizolam Impurity 14 (CAS 40054-57-7)
- Etizolam Impurity 7 (CAS 91663-72-8)
- Etizolam Impurity 4 (CAS 110753-14-5)
- Etizolam Impurity 15 (CAS 51687-58-2)
- Etizolam Impurity 20 (CAS 50508-61-7)
- Etizolam Impurity 8 (CAS 54123-29-4)
- Etizolam Impurity 27 (CAS CATO-C4X-350927)
- Etizolam Impurity 5 (CAS CATO-C4X-35095)
Recommended Standards
- 6-Chloro-4-(prop-2-en-1-ylsulfanyl)-8-thia-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene (CAS 478029-83-3)
- 1-(5-(4-(tert-Butyl)phenyl)-4-chlorothiophen-2-yl)ethan-1-one (CAS 1309597-88-3)
- 5-(4-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidine-4(3H)-thione (CAS 500198-74-3)
- 1-(4-Chlorophenyl)-3-(p-tolylthio)propan-1-ol (CAS 338391-85-8)
- Umeclidinium Impurity 5 (CAS CATO-C4X-13395)
- Betahistine Impurity 16 (CAS CATO-C4X-183816)
- Halometasone impurity 11 (CAS CATO-C4X-144611)
- 3,6-Dimethyl-2,3,4,5-tetrahydropyridazine-3-carboxylic acid (CAS 90048-20-7)
- (S)-2-Amino-N-(3-bromobenzyl)-N-cyclopropyl-3-methylbutanamide (CAS 1354000-42-2)
- rac cis-Moxifloxacin-d4 (CAS 2596386-23-9)
- Pyrimethamine-D3 (CAS 1189936-99-9)
- 2-Benzyl-2H-tetrazole-5-carboxylic acid (CAS 55408-13-4)
- 1019186-62-9 6,6-Dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxylic acid (CAS 1019186-62-9)
- Allo-D-Ile27-Tirzepatide (CAS CATO-CPTD788961)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com