Maprotiline EP impurity C HCl CAS 92202-51-2
| CAS No. | 92202-51-2 |
| Molecular Formula | C19H21N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Maprotiline EP impurity C HCl (CAS 92202-51-2), a pharmacopoeial impurity reference standard (molecular formula C19H21NHCl, MW 299.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Maprotiline EP impurity C HCl (C19H21NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 299.84 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21N HCl |
| Molecular Weight | 299.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Maprotiline Standards
- Maprotiline (CAS 10262-69-8)
- Maprotiline Hydrochloride (CAS 10347-81-6)
- Maprotiline Hydrochloride EP Impurity B (CAS 1648814-39-4)
- Maprotiline-d5 Hydrochloride (CAS 1794942-12-3)
- Maprotiline EP impurity E (CAS 23941-38-0)
- Maprotiline EP impurity E HCl (CAS 23941-45-9)
- Maprotiline EP impurity B HCl (CAS 2724727-05-1)
- (E)-Maprotiline EP Impurity A (CAS 38849-09-1)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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