3-(3-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid CAS 926247-48-5
| CAS No. | 926247-48-5 |
| Molecular Formula | C15H9ClN2O4 |
| Molecular Weight | 316.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(3-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (CAS 926247-48-5), molecular formula C15H9ClN2O4 and molecular weight 316.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid (C15H9ClN2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 3-(3-Chlorophenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H9ClN2O4 |
| Molecular Weight | 316.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- N-(4-Chlorophenyl)-5-nitro-1H-indazole-1-carboxamide (CAS 89331-91-9)
- (2Z)-3-(4-Chlorophenyl)-2-cyano-N-(4-fluorophenyl)-3-hydroxyprop-2-enamide (CAS 866151-39-5)
- 1-(2-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-81-1)
- 1-(3-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618383-16-7)
- 1-(4-Chlorophenyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-74-2)
- 3-(4-Chlorophenyl)-1-((4-fluorophenyl)amino)-1H-pyrrole-2,5-dione (CAS 271254-37-6)
- 3-(4-Chlorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-55-9)
- 3-(4-Chlorophenyl)-1-(4-fluorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-39-9)
Recommended Standards
- 2-Chloro-N-[3-cyano-4,5-bis(furan-2-yl)furan-2-yl]acetamide (CAS 554404-36-3)
- 6-CHLOROPURINE-9-ß-D-GLUCOSIDE (CAS 66981-23-5)
- 2-(7-Chloro-3-hydroxy-4-oxo-3,4-dihydroquinazolin-2-yl)benzoic acid (CAS 860787-85-5)
- 1-(4-Chlorobenzyl)-5-nitroindoline-2,3-dione (CAS 278803-50-2)
- 1,3,5-Trimethylcyclohexan-1-amine (CAS 259734-12-8)
- Salbutamol-d3 (CAS 1219798-60-3)
- 2-Propenenitrile, polymer with 1,3-butadiene and 2-methyl-1,3-butadiene (CAS 25135-90-4)
- 6-methyl-4-(trifluoromethyl)pyridazin-3-amine (CAS 1379378-80-9)
- 5-Bromo-7-iodobenzo[d][1,3]dioxol-4-amine (CAS 643086-28-6)
- Methyl 7-methoxychromane-3-carboxylate (CAS 885271-74-9)
- 2-Methoxyphenazine (CAS 2876-18-8)
- 4-Bromo-3-methyl-N-(pyridin-2-ylmethyl)aniline (CAS 418784-76-6)
- N-Cyclohexyl-2-Benzothiazolylsulfenamide (CAS 95-33-0)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com