Alfuzosin EP Impurity G CAS 928780-95-4
| CAS No. | 928780-95-4 |
| Molecular Formula | C24H30N8O4 |
| Molecular Weight | 494.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Alfuzosin EP Impurity G (CAS 928780-95-4), a pharmacopoeial impurity reference standard (molecular formula C24H30N8O4, MW 494.55 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Alfuzosin EP Impurity G (C24H30N8O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30N8O4 |
| Molecular Weight | 494.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 8 |
Related Alfuzosin Standards
- Alfuzosin Impurity 10 (CAS CATO-C4X-153610)
- Alfuzosin-d7 (CAS 1346746-88-0)
- Alfuzosin-D6 (CAS 1006717-31-2)
- Alfuzosin EP Impurity C (CAS 98902-34-2)
- Alfuzosin EP Impurity A (CAS 98902-36-4)
- Alfuzosin EP Impurity E (CAS 1026411-59-5)
- Alfuzosin EP Impurity D (CAS 76362-29-3)
- Alfuzosin EP Impurity F (CAS 19216-53-6)
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