Isothiazolo[4,5-b]pyrazin-3-amine CAS 92914-68-6
| CAS No. | 92914-68-6 |
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Isothiazolo[4,5-b]pyrazin-3-amine.
Isothiazolo[4,5-b]pyrazin-3-amine (CAS 92914-68-6), molecular formula C5H4N4S and molecular weight 152.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Isothiazolo[4,5-b]pyrazin-3-amine (C5H4N4S) is characterized by a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H4N4S |
| Molecular Weight | 152.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1983 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Isothiazolo Standards
- Isothiazolo[5,4-b]pyridin-3-ol (CAS 4337-60-4)
- Isothiazolo[5,4-d]pyrimidin-4-ol (CAS 1498711-48-0)
- Isothiazolo[4,5-c]pyridin-3-amine (CAS 1367990-09-7)
- Isothiazolo[3,4-c]pyridin-3-amine (CAS 150364-74-2)
- Isothiazolo[5,4-c]pyridin-3-amine (CAS 150364-77-5)
- Isothiazolo[4,3-b]pyridin-3-ylamine (CAS 42242-13-7)
- Isothiazolo[4,5-b]pyridin-3-amine (CAS 2089325-25-5)
- Isothiazolo[5,4-b]pyridin-3-amine (CAS 56891-64-6)
Recommended Standards
- 7h-Purine-8-thiol (CAS 583-40-4)
- Thiazolo[4,5-d]pyrimidin-2-amine (CAS 857970-35-5)
- 5-Thien-2-yl-2H-tetrazole (CAS 59541-58-1)
- Thiazolo[4,5-d]pyrimidin-7-amine (CAS 2168138-70-1)
- (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-fluorophenyl)methanone (CAS 914350-54-2)
- 5-Methyl-4-(4-morpholino-3-(morpholinosulfonyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 893779-24-3)
- (R,2E,4E,8Z)-Methyl 6-((tert-butyldiphenylsilyl)oxy)tetradeca-2,4,8-trienoate (CAS 116279-81-3)
- N-(4-(N-Cyclohexyl-N-methylsulfamoyl)phenyl)furan-2-carboxamide (CAS 713507-02-9)
- 4-Chloro-3-(4,5-dimethyl-4h-1,2,4-triazol-3-yl)aniline (CAS 1248978-56-4)
- Disulfoton-Sulfone (CAS 2497-06-5)
- 4-Fluoro-N-(1-(4-methoxybenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-90-8)
- Methyl 3-chloro-4-oxo-1,4-dihydroquinoline-6-carboxylate (CAS 1264209-58-6)
- 6-Methyl-2-{3-methyl-5-[(4-methylphenyl)amino]-1H-pyrazol-1-yl}-1,4-dihydropyrimidin-4-one (CAS 882231-37-0)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
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