2-Chloro-2,5-difluoroacetophenone CAS 60468-36-2
| CAS No. | 60468-36-2 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-2,5-difluoroacetophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-2,5-difluoroacetophenone (CAS 60468-36-2) is a high-purity analytical reference standard with the molecular formula C8H5ClF2O and a molecular weight of 190.57 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-2,5-difluoroacetophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4'-Chloro-2',6'-difluoroacetophenone (CAS 1017777-45-5)
- 1-(2-Chloro-4,5-difluorophenyl)ethanone (CAS 121872-94-4)
- 1-(4-Chloro-3,5-difluorophenyl)ethan-1-one (CAS 1256352-85-8)
- 2-(2-Chloro-3,6-difluorophenyl)acetaldehyde (CAS 1256477-62-9)
- 2-(3-Chloro-2,6-difluorophenyl)acetaldehyde (CAS 1256479-70-5)
- 1-(6-Chloro-2,3-difluorophenyl)ethan-1-one (CAS 1373920-86-5)
- 1-(3-Chloro-2,4-difluorophenyl)ethanone (CAS 154258-06-7)
- 5-Chloro-2-(difluoromethyl)benzaldehyde (CAS 1554368-81-8)
Recommended Standards
- 2-Chloro-1-(3,5-difluorophenyl)ethan-1-one (CAS 920023-60-5)
- Voriconazole Impurity N1 (CAS 929249-84-3)
- 2-Chloro-1-(2,3-difluorophenyl)ethanone (CAS 929249-82-1)
- 2,3 - Difluoro - 4 - methylbenzoyl chloride 2,3-Difluoro-4-methyl-benzoyl chloride 2,3-difluoro-p-toluoyl chloride 261763-38-6 benzoyl chloride, 2,3-difluoro-4-methyl- (CAS 261763-38-6)
- 10-Hydroxyaloin B (CAS 134863-92-6)
- Diamminedichloropalladium (CAS 14323-43-4)
- 4-[3-(tert-Butyl)phenoxy]-3-fluorophenylamine (CAS 946699-13-4)
- 5-Norbornene-2-methylamine (mixture of isomers) (CAS 95-10-3)
- 2-Chloro-n-(8-nitro-3,4-dihydro-2h-1,5-benzodioxepin-7-yl)acetamide (CAS 949984-49-0)
- 2-(1-Methyl-1H-indazol-5-yl)acetic acid (CAS 1176749-66-8)
- 5-Chloro-2-[(4-methylbenzyl)oxy]benzoyl chloride (CAS 1160260-18-3)
- 2-Chloro-N-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)-acetamide 757220-20-5 9281AE C11H12ClNO3 (CAS 757220-20-5)
- [(4-Bromo-3-methylbutoxy)methyl]benzene (CAS 87974-13-8)
- Casein Kinase II Receptor Peptide (CAS 198481-81-1)
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