Pimavanserin Impurity 5 CAS 932724-63-5
| CAS No. | 932724-63-5 |
| Molecular Formula | C21H18F3N |
| Molecular Weight | 341.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Pimavanserin Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Pimavanserin Impurity 5 (CAS 932724-63-5, C21H18F3N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pimavanserin Impurity 5 (C21H18F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C21H18F3N |
| Molecular Weight | 341.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pimavanserin Standards
- Pimavanserin impurity 62 (CAS CATO-C4X-193862)
- Pimavanserin Impurity 2 (CAS 103907-97-7)
- Pimavanserin Impurity 12 (CAS CATO-C4X-193812)
- Pimavanserin Impurity 44 (CAS CATO-C4X-193844)
- Pimavanserin Impurity 39 (CAS CATO-C4X-193839)
- Pimavanserin Impurity 40 (CAS CATO-C4X-193840)
- Pimavanserin Impurity 50 (CAS CATO-C4X-193850)
- Pimavanserin Impurity 27 (CAS CATO-C4X-193827)
Recommended Standards
- Tofacitinib Impurity 177 (CAS CATO-C4X-1079177)
- Ethyl 2-(methylthio)-5-oxo-8-phenyl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate (CAS 100426-81-1)
- 596-43-0 Benzene, 1,1',1''-(bromomethylidyne)tris- 2-Bromo-1,1,1-triphenylethane Methane, bromotriphenyl- 4-05-00-02500 (Beilstein Handbook Reference) AI3-51274 BRN 1878494 Bromotriphenylmethane EINECS 209-884-4 NSC 66464 Triphenylmethyl bromide Trityl bromide (CAS 596-43-0)
- Methyl 3-{[(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-yliden)methyl]amino}-2-thiophenecarboxylate (CAS 1025619-73-1)
- Upadacitinib Impurity 113 (CAS CATO-C4X-2405113)
- Furazolidone Impurity 3 (CAS CATO-C4X-29013)
- Atorvastatin EP Impurity C Calcium Salt (CAS 693793-53-2)
- 1,3-Thiazole-2-carboxamide (CAS 16733-85-0)
- Atrasentan Impurity 116 (CAS 220584-55-4)
- 4-(2-Amino-1-(pyridin-3-yl)ethyl)thiomorpholine 1,1-dioxide (CAS 1154976-31-4)
- 2-(5-oxopyrrolidin-2-yl)propanoic acid (CAS 24454-63-5)
- Ethyl 2-chloro-2-(3-chloro-4-fluorophenyl)acetate (CAS 1531504-82-1)
- Revefenacin impurity 94 (CAS CATO-C4X-203194)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com