Atorvastatin EP Impurity C Calcium Salt CAS 693793-53-2
| CAS No. | 693793-53-2 |
| Molecular Formula | 2*C33H33F2N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Atorvastatin EP Impurity C Calcium Salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Atorvastatin EP Impurity C Calcium Salt (CAS 693793-53-2, C33H33F2N2O5Ca) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Atorvastatin EP Impurity C Calcium Salt (C33H33F2N2O5Ca) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.5, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 615.71 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | 2*C33H33F2N2O5 Ca |
| Molecular Weight | 615.71 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Atorvastatin Standards
- Atorvastatin Impurity 22 (CAS 1035205-25-4)
- Atorvastatin Calcium Propylene Glycol Solvate (CAS 1040350-07-9)
- Atorvastatin Lactone Diepoxide (CAS 1046118-40-4)
- Atorvastatin Lactam calcium Salt Impurity (CAS 1046118-41-5)
- Atorvastatin Impurity 86 (CAS 1046118-44-8)
- Atorvastatin Impurity 141 Calcium Salt (CAS 1046378-58-8)
- Atorvastatin Impurity 76 (CAS 1099474-28-8)
- Atorvastatin EP Impurity F(Calcium Salt) (CAS 1105067-87-5)
Recommended Standards
- Rosuvastatin Impurity 150 (CAS CATO-C4X-1169150)
- Tiotropium impurity 48 (CAS CATO-C4X-176448)
- Mianserin Impurity 92 (CAS CATO-C4X-136992)
- N-(2,5-dimethoxybenzyl)-1-(2-methoxyphenyl)methanamine hydrobromide (CAS 1609404-02-5)
- (Z)-4-((4-Benzoylphenyl)amino)-4-oxobut-2-enoic acid (CAS 174603-69-1)
- 2-(4-Bromophenyl)-4,5-dichlorothiazole (CAS 1355231-32-1)
- 2,2-Difluoro-2-(3-methylpyridin-4-yl)acetic acid (CAS 1504827-81-9)
- 4-((4-(2-Bromoethoxy)phenyl)sulfonyl)morpholine (CAS 874754-28-6)
- Bifendate impurity 10 (CAS CATO-C4X-255510)
- HA Peptide (CAS 92000-76-5)
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