Moxifloxacin impurity 178 CAS 934841-13-1
| CAS No. | 934841-13-1 |
| Molecular Formula | C20H22FN3O4 |
| Molecular Weight | 387.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Moxifloxacin impurity 178 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Moxifloxacin impurity 178 (CAS 934841-13-1, C20H22FN3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Moxifloxacin impurity 178 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 387.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H22FN3O4 |
| Molecular Weight | 387.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Moxifloxacin Standards
- Moxifloxacin impurity 177 (CAS 1293488-61-5)
- Moxifloxacin EP Impurity E (CAS 721970-36-1)
- Moxifloxacin EP Impurity A (CAS 151213-15-9)
- Moxifloxacin Impurity 20 (CAS 959347-97-8)
- Moxifloxacin Impurity 56 (CAS CATO-C4X-1074156)
- Moxifloxacin impurity 167 (CAS CATO-C4X-1074167)
- Moxifloxacin Impurity 57 (CAS CATO-C4X-1074157)
- Moxifloxacin Impurity 47 (CAS 2315304-27-7)
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