Moxifloxacin Impurity 57 CAS CATO-C4X-1074157
| CAS No. | CATO-C4X-1074157 |
| Molecular Formula | C19H21ClFN3O2 |
| Molecular Weight | 377.84 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Moxifloxacin Impurity 57 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Moxifloxacin Impurity 57 (CAS CATO-C4X-1074157, C19H21ClFN3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Moxifloxacin Impurity 57 (C19H21ClFN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21ClFN3O2 |
| Molecular Weight | 377.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Moxifloxacin Standards
- Moxifloxacin Impurity 196 (CAS CATO-C4X-1074196)
- Moxifloxacin impurity 167 (CAS CATO-C4X-1074167)
- Moxifloxacin impurity 129 (CAS CATO-C4X-1074129)
- Moxifloxacin Impurity 20 (CAS 959347-97-8)
- Moxifloxacin Impurity 158 (CAS CATO-C4X-1074158)
- Moxifloxacin impurity 177 (CAS 1293488-61-5)
- Moxifloxacin impurity 178 (CAS 934841-13-1)
- Moxifloxacin EP Impurity E (CAS 721970-36-1)
Recommended Standards
- 416901-58-1 COX-2 Inhibitor I (CAS 416901-58-1)
- 4-(4-Chlorophenyl)-5-(3,4,5-trimethoxyphenyl)-4h-1,2,4-triazole-3-thiol (CAS 70452-52-7)
- N-(3-Chloro-4-methoxybenzyl)-4-(4-fluorophenyl)tetrahydro-1(2H)-pyrazinecarboxamide (CAS 866137-32-8)
- 4-Chloro-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)benzenesulfonamide (CAS 301314-62-5)
- Ceftibuten Impurity 1 (CAS CATO-C4X-18901)
- Sertraline EP Impurity E (CAS 611-71-2)
- Mesna EP Impurity D sodium salt (CAS 16208-51-8)
- 4-Hydroxyheptanoate Sodium (CAS 17587-29-0(free base))
- 2-((Cyclohexylmethyl)amino)-4-methylpentan-1-ol (CAS 1248324-86-8)
- N-(3-(3-Hydroxyprop-1-yn-1-yl)pyridin-2-yl)pivalamide (CAS 1203499-45-9)
- (4-METHYLPIPERAZIN-1-YL)(P-TOLYL)METHANONE (CAS 219989-25-0)
- 4-(Chloromethyl)-2,6-difluoropyridine (CAS 1227584-54-4)
- (4-(((Tert-butoxycarbonyl)(cyclohexyl)amino)methyl)-2-fluorophenyl)boronic acid (CAS 1704097-11-9)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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