3,3-Difluoropiperidin-1-amine CAS 935260-59-6
| CAS No. | 935260-59-6 |
| Molecular Formula | C5H10F2N2 |
| Molecular Weight | 136.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,3-Difluoropiperidin-1-amine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3,3-Difluoropiperidin-1-amine (CAS 935260-59-6), a certified reference material (molecular formula C5H10F2N2, MW 136.14 g/mol) for analytical method development and quality control.
The molecular framework of 3,3-Difluoropiperidin-1-amine (C5H10F2N2) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H10F2N2 |
| Molecular Weight | 136.14 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoropiperidin Standards
- (3R)-5,5-difluoropiperidin-3-amine (CAS 2580094-38-6)
- (3S)-5,5-difluoropiperidin-3-amine (CAS 2580114-26-5)
- 4,4-Difluoropiperidin-1-amine (CAS 811441-26-6)
- 4,4-Difluoropiperidin-3-ol (CAS 1187087-19-9)
- 3,3-Difluoropiperidin-4-ol (CAS 1239596-54-3)
- 5,5-Difluoropiperidin-3-ol (CAS 1258639-09-6)
- (S)-4,4-difluoropiperidin-3-ol (CAS 1620724-08-4)
- (R)-3,3-Difluoropiperidin-4-ol (CAS 2199320-91-5)
Recommended Standards
- 3,3-Difluorocyclohexan-1-ol (CAS 94099-53-3)
- 3,5-difluoropyridin-2-amine (CAS 732306-31-9)
- 3,3-difluoro-2,2-dimethylbutanal (CAS 1996581-55-5)
- 3,6-difluoropyridin-2-amine (CAS 944799-22-8)
- 9,10-Dioxo-9,10-dihydroanthracene-2-carboxamide (CAS 7223-72-5)
- N-Trityl Losartan Carboxylic Acid (CAS 960231-60-1)
- (1R,5R)-3,3,5-Trimethylcyclohexanamine (CAS 1821723-32-3)
- P,P-Diphenylphosphinothioic amide (CAS 17366-80-2)
- (4Z)-1-(4,5-Dihydro-1,3-thiazol-2-yl)-3-methyl-4-(2-phenylhydrazin-1-ylidene)-4,5-dihydro-1H-pyrazol-5-one (CAS 338402-55-4)
- (4-Chloroquinolin-7-yl)methanol (CAS 178984-44-6)
- [5-fluoro-2-(1H-1,2,4-triazol-1-yl)phenyl]methanol (CAS 1096329-29-1)
- 1-(4-Bromo-2-fluorophenyl)ethan-1-amine hydrochloride (CAS 1909319-65-8)
- Benzyl 3-((2-amino-N-methylacetamido)methyl)piperidine-1-carboxylate (CAS 1353959-86-0)
- Pancreatic Polypeptide (31-36) Free Acid, human (CAS 192432-73-8)
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