Ruxolitinib Impurity N6 CAS 941685-39-8
| CAS No. | 941685-39-8 |
| Molecular Formula | C23H32N6OSi |
| Molecular Weight | 436.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ruxolitinib Impurity N6 (CAS 941685-39-8, C23H32N6OSi) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ruxolitinib Impurity N6 (C23H32N6OSi) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ruxolitinib Impurity N6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H32N6OSi |
| Molecular Weight | 436.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity N4 (CAS 941685-40-1)
- Ruxolitinib Impurity 186 (CAS 941685-41-2)
- Ruxolitinib Impurity 24 (CAS CATO-C4X-205824)
- Ruxolitinib Impurity 25 (CAS CATO-C4X-205825)
- Ruxolitinib Impurity 56 (CAS CATO-C4X-205856)
- Ruxolitinib Impurity 173 (CAS 1236032-96-4)
- Ruxolitinib Impurity 55 (CAS CATO-C4X-205855)
- Ruxolitinib Impurity 8 Trifluoroacetate (CAS 2606144-44-7(free base))
Recommended Standards
- tert-butyl N-(tert-butoxycarbonylamino)-N-[3-(4-tert-butylphenyl)-1-bicyclo[1.1.1]pentanyl]carbamate (CAS 2149634-60-4)
- 4-(Pentyloxy)phenyl 4-(trans-4-pentylcyclohexyl)benzoate (CAS 84601-01-4)
- 1,3-Bis(diphenylphosphino)propane 6737-42-4 1,3-BIS(DIPHENYLPHOSPHINE)PROPANE;1,3-BIS(DIPHENYLPHOSPHINO)PROPANE;1,3-BIS(DIPHENYPHOSPHINO)PROPANE;DPPP;PROPYLENEBIS(DIPHENYLPHOSPHINE);TRIMETHYLENEBIS(DIPHENYLPHOSPHINE);[3-(DIPHENYLPHOSPHANYL)PROPYL]DIPHENYLPHOSPHANE GC10105 (CAS 6737-42-4)
- 4-(Hexyloxy)phenyl 4-(trans-4-butylcyclohexyl)benzoate (CAS 89331-95-3)
- Atracurium Impurity 116 (CAS CATO-C4X-1850116)
- Acetylcysteine Impurity 22 (CAS CATO-C4X-153222)
- Betamethasone impurity 53 (CAS CATO-C4X-143753)
- Methyl 3-(3,5-Difluorophenyl)-3-oxopropionate (CAS 1530834-98-0)
- Dihydroxytartaric Acid Disodium Salt (CAS 866-17-1)
- (S)-4-(1-amino-2,2-dimethylpropyl)-2-chloroaniline (CAS 1388632-76-5)
- cis-3-(Methoxycarbonyl)cyclohexanecarboxylic Acid (CAS 733742-58-0)
- 2-{5-bromopyrrolo[2,1-f][1,2,4]triazin-7-yl}ethan-1-amine (CAS 1781830-19-0)
- Ethyl 3-amino-5-methoxybenzofuran-2-carboxylate (CAS 901138-46-3)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com