4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one CAS 618075-97-1
| CAS No. | 618075-97-1 |
| Molecular Formula | C27H25FN2O3 |
| Molecular Weight | 444.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618075-97-1), molecular formula C27H25FN2O3 and molecular weight 444.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (C27H25FN2O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H25FN2O3 |
| Molecular Weight | 444.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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- 5-[((3Z)-5-Fluoro-2-oxo-1,2-dihydroindol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxylic acid [2-hydroxy-3-(morpholin-4-yl)propyl]amide (CAS 452104-85-7)
- 7-fluoro-1,4-dihydro-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-6-iodo-4-oxo-3-Quinolinecarboxylic acid ethyl ester (CAS 697762-60-0)
- 3-(4-Fluoro-3-nitrophenyl)-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796920-47-2)
- 4-(3-Fluoro-4-methylbenzoyl)-3-hydroxy-5-(4-nitrophenyl)-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 618073-84-0)
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- 5-Fluoro-3-(5-fluoro-4-(methylsulfinyl)pyrimidin-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 1259279-58-7)
Recommended Standards
- 2-(2-(2-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)thiazol-4-yl)acetamido)benzamide (CAS 941874-54-0)
- Boc-arg(mbS)-oh (CAS 58810-09-6)
- 2,5-Dimethoxy-N-(1-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)cyclohexyl)benzenesulfonamide (CAS 1396799-72-6)
- Fmoc-beta-(benzothiazol-2-yl)-L-alanine (CAS 959583-56-3)
- Amino-PEG3-C2-sulfonic acid (CAS 1817735-43-5)
- 6-(1-methyl-1H-pyrazol-4-yl)-2,3-dihydropyridazin-3-one (CAS 1100598-49-9)
- 2-amino-6-bromo-benzaldehyde (CAS 135484-74-1)
- (3R)-1-(Propan-2-yl)pyrrolidin-3-amine (CAS 935534-43-3)
- 1-Methyl-2-phenyl-1,2,3,4-tetrahydroquinolin-4-ol (CAS 918165-54-5)
- n-(2-Methoxyethyl)-5-nitropyridin-2-amine (CAS 74037-56-2)
- 1-Cyclopentenecarboxylic Acid (CAS 1560-11-8)
- Methyl 4-methylquinoline-2-carboxylate (CAS 80109-83-7)
- methyl 2-(1-aminocyclopentyl)acetate hydrochloride (CAS 1224474-26-3)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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