Ponatinib Impurity 51 CAS 94224-92-7
| CAS No. | 94224-92-7 |
| Molecular Formula | C9H9IO2 |
| Molecular Weight | 276.07 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ponatinib Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ponatinib Impurity 51 (CAS 94224-92-7), a pharmacopoeial impurity reference standard (molecular formula C9H9IO2, MW 276.07 g/mol) used for the identification and quantification of trace impurities in APIs.
Ponatinib Impurity 51 (C9H9IO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H9IO2 |
| Molecular Weight | 276.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1983 |
| Halogen Content | I-containing |
Related Ponatinib Standards
- Ponatinib Impurity 50 (CAS 1781021-72-4)
- Ponatinib impurity 7 (CAS 1300690-48-5)
- Ponatinib impurity 4 (CAS 694499-26-8)
- Ponatinib Impurity 56 (CAS CATO-C4X-226956)
- Ponatinib Impurity 57 (CAS CATO-C4X-226957)
- Ponatinib Impurity 38 (CAS 2755819-36-2)
- Ponatinib Impurity 52 (CAS 31719-79-6)
- Ponatinib Impurity 30 (CAS CATO-C4X-226930)
Recommended Standards
- N-(5-iodopyridin-2-yl)propionamide (CAS 842116-47-6)
- 1-(2-bromoethoxy)-4-methoxy-2-nitrobenzene (CAS 1016508-18-1)
- N-(5-Iodo-6-methylpyridin-2-yl)acetamide (CAS 706775-95-3)
- Ethyl 4-(2-Bromoacetyl)-5-methylisoxazole-3-carboxylate (CAS 115697-68-2)
- Galantamine EP Impurity C (CAS 21133-52-8)
- Empagliflozin impurity 216 (CAS CATO-C4X-1065216)
- Rasagiline Impurity 31 (CAS CATO-C4X-191351)
- 3-{[2-(1-Cyclohexen-1-yl)ethyl]amino}-N-ethylpropanamide (CAS 1040691-15-3)
- 2-((tert-Butoxycarbonyl)amino)-3-(5-methyl-1H-indol-3-yl)propanoic acid (CAS 142847-21-0)
- 2-(3-(Cyclopentylcarbamoyl)-2-oxopyridin-1(2H)-yl)acetic acid (CAS 1361114-86-4)
- 3-Chloro-4-cyclopropoxy-2-iodopyridine (CAS 1243345-83-6)
- (5-Chloro-1h-1,3-benzodiazol-2-yl)(phenyl)methanol (CAS 17753-02-5)
- 2-(2,3-Difluoro-4-methylphenyl)acetic acid (CAS 261763-47-7)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com