Tolvaptan Impurity 50 CAS 942619-74-1
| CAS No. | 942619-74-1 |
| Molecular Formula | C26H26ClN2O6P |
| Molecular Weight | 528.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tolvaptan Impurity 50 (CAS 942619-74-1), a pharmacopoeial impurity reference standard (molecular formula C26H26ClN2O6P, MW 528.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tolvaptan Impurity 50 (C26H26ClN2O6P) contains a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 14.5, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 528.92 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26ClN2O6P |
| Molecular Weight | 528.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 104 (CAS CATO-C4X-1955104)
- Tolvaptan Impurity 62 (CAS 2657689-30-8)
- Tolvaptan Impurity 57 (CAS CATO-C4X-195557)
- Tolvaptan Impurity 75 (CAS CATO-C4X-195575)
- Tolvaptan Impurity 105 (CAS 942619-93-4)
- Tolvaptan Impurity 101 (CAS CATO-C4X-1955101)
- Tolvaptan Impurity 94 (CAS CATO-C4X-195594)
- Tolvaptan Impurity 48 (CAS CATO-C4X-195548)
Recommended Standards
- (9E)-Lumefantrine (CAS 1456736-33-6)
- 2-(4-Chlorophenyl)-N-[(1Z)-{[(3-methoxyphenyl)methoxy]imino}methyl]-2-[3-(trifluoromethyl)quinoxalin-2-yl]acetamide (CAS 338391-62-1)
- (E)-1,2-bis(4-dodecylthiophen-2-yl)ethene (CAS 306769-54-0)
- 2-(4-Chlorophenyl)-N-[(1E)-{[(4-methoxyphenyl)methoxy]imino}methyl]-2-[3-(trifluoromethyl)quinoxalin-2-yl]acetamide (CAS 338391-63-2)
- Apixaban Impurity 156 (CAS CATO-C4X-1088156)
- Memantine impurity 57 (CAS CATO-C4X-105857)
- Baloxavir Impurity 14 (CAS CATO-C4X-210814)
- 4-Methyl-5-oxo-2,5-dihydrofuran-3-carbohydrazide (CAS 137910-48-6)
- (2-isocyanatopropyl)benzene (CAS 65535-55-9)
- 1-(3-methyl-1,2-oxazol-5-yl)ethan-1-amine (CAS 543713-47-9)
- tert-Butyl 2-Butynoate (CAS 218457-99-9)
- 4-(Methylsulfonyl)piperazine-1-sulfonyl chloride (CAS 1339024-98-4)
- 4-fluoroisoindoline-1,3-dione (CAS 51108-29-3)
- Liraglutide Impurity 31 (CAS CATO-C4X-199231)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com