Tolvaptan Impurity 105 CAS 942619-93-4
| CAS No. | 942619-93-4 |
| Molecular Formula | C26H26ClN2O5P |
| Molecular Weight | 512.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 512.92 g/mol gives Tolvaptan Impurity 105 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tolvaptan Impurity 105 (CAS 942619-93-4) is a certified pharmaceutical impurity reference standard with the molecular formula C26H26ClN2O5P and a molecular weight of 512.92 g/mol.
Tolvaptan Impurity 105 (C26H26ClN2O5P) contains a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H26ClN2O5P |
| Molecular Weight | 512.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 75 (CAS CATO-C4X-195575)
- Tolvaptan Impurity 62 (CAS 2657689-30-8)
- Tolvaptan Impurity 104 (CAS CATO-C4X-1955104)
- Tolvaptan Impurity 50 (CAS 942619-74-1)
- Tolvaptan Impurity 48 (CAS CATO-C4X-195548)
- Tolvaptan impurity 112 (CAS CATO-C4X-1955112)
- Tolvaptan Impurity 25 (CAS 2921676-63-1)
- Tolvaptan Impurity 57 (CAS CATO-C4X-195557)
Recommended Standards
- N-[4-[(2-Amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-1,2-dihydro-2-oxo-3-pyridinecarboxamide (CAS 1025720-94-8)
- 1-[4-chloro-3-(trifluoromethyl)benzenesulfonyl]-4-[4-(5-methyl-1H-pyrazol-1-yl)benzoyl]piperazine (CAS 1007647-73-5)
- Triphenylantimony dibromide, 98+% (CAS 1538-59-6)
- (T-4)-[[N1(S),N2(S),1R,2R]-N1,N2-Bis(phenylmethyl)-1,2-cyclohexanediamine-κN1,κN2]dibromonickel (CAS 952650-55-4)
- Esmolol Impurity 40 (CAS 61389-68-2)
- Oseltamivir Impurity 179 (CAS CATO-C4X-1720179)
- Sulpiride Impurity 22 (CAS CATO-C4X-187622)
- [(2,5-difluorophenyl)methyl]hydrazine (CAS 887595-45-1)
- 1-(3,4-Dichlorophenyl)-4,5-dihydro-1H-pyrazol-3-amine, >97% (CAS 66000-42-8)
- [1-(aminomethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]methanol (CAS 2137574-46-8)
- 5-Bromo-7-fluoro-1-benzofuran-2-carbaldehyde (CAS 1480288-05-8)
- Imatinib Impurity 85 (CAS 909342-95-6)
- Dronedarone Impurity 16 (CAS CATO-C4X-109216)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com