Lubiprostone impurity 6 CAS 945651-35-4
| CAS No. | 945651-35-4 |
| Molecular Formula | C27H38F2O5 |
| Molecular Weight | 480.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lubiprostone impurity 6.
CATO supplies Lubiprostone impurity 6 (CAS 945651-35-4), a pharmacopoeial impurity reference standard (molecular formula C27H38F2O5, MW 480.58 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H38F2O5, Lubiprostone impurity 6 contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 480.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lubiprostone impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H38F2O5 |
| Molecular Weight | 480.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Lubiprostone Standards
- Lubiprostone Impurity 12 (CAS 1447733-80-3)
- Lubiprostone Impurity 28 (CAS CATO-C4X-113628)
- Lubiprostone Impurity 21 (CAS CATO-C4X-113621)
- Lubiprostone impurity 8 (CAS 136790-79-9)
- Lubiprostone Impurity 14 (CAS CATO-C4X-113614)
- Lubiprostone impurity 5 (CAS CATO-C4X-11365)
- Lubiprostone Impurity 23 (CAS CATO-C4X-113623)
- Lubiprostone Impurity 11 (CAS CATO-C4X-113611)
Recommended Standards
- N-tert-Butyl-2-(4-methylbenzenesulfonamido)-N-[(phenylcarbamoyl)amino]benzamide (CAS 866009-78-1)
- Sulfatinib (CAS 1308672-74-3)
- 3-(4-Tosylpiperazine-1-carbonyl)-7,8,9,10-tetrahydroazepino[2,1-b]quinazolin-12(6H)-one (CAS 854134-90-0)
- Tr-PEG5-OH (CAS 141282-24-8)
- Isavuconazole Impurity 213 (CAS CATO-C4X-1236213)
- Vazegepant Impurity 8 (CAS CATO-C4X-32008)
- Lopinavir EP Impurity Q (CAS 667904-94-1)
- 2-Pentafluoroethyl-3-trifluoromethyl-6-chloropyridine (CAS 1246466-64-7)
- 3,6-Dimethoxybenzene-1,2-diamine (CAS 40328-95-8)
- Indigodisulfonic acid dipotassium salt (CAS 13725-33-2)
- 1-Phenyl-4-(o-tolyl)-1H-pyrazole-5-carboxamide (CAS 324009-00-9)
- 2-Bromopropionic Acid Benzyl Ester (CAS 3017-53-6)
- (2S,6R)-2-amino-2-(2-chlorophenyl)-6-fluoro-1-methoxycyclohexan-1-ol (CAS CATO-C3D-262376)
- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com