Vazegepant Impurity 8 CAS CATO-C4X-32008

Purity ＞95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-32008
Molecular FormulaC48H57N11O6
Molecular Weight884.04 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Vazegepant Impurity 8 CAS CATO-C4X-32008 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vazegepant Impurity 8.

CATO supplies Vazegepant Impurity 8 (CAS CATO-C4X-32008), a pharmacopoeial impurity reference standard (molecular formula C48H57N11O6, MW 884.04 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Vazegepant Impurity 8 (C48H57N11O6) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 26.0, corresponding to approximately 26 ring(s) or double-bond equivalent(s). With a molecular weight of 884.04 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC48H57N11O6
Molecular Weight884.04 g/mol
Purity＞95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)26.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms11

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