Bumetanide Impurity 61 CAS 94610-14-7

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.94610-14-7
Molecular FormulaC17H20N2O6S
Molecular Weight380.42 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Bumetanide Impurity 61 CAS 94610-14-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 380.42 g/mol gives Bumetanide Impurity 61 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bumetanide Impurity 61 (CAS 94610-14-7) is a certified pharmaceutical impurity reference standard with the molecular formula C17H20N2O6S and a molecular weight of 380.42 g/mol.

The molecular framework of Bumetanide Impurity 61 (C17H20N2O6S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Bumetanide Impurity 61 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H20N2O6S
Molecular Weight380.42 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1984
Nitrogen Atoms2
Sulfur Atoms1

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