1-(4-Fluorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxamide CAS 946352-89-2
| CAS No. | 946352-89-2 |
| Molecular Formula | C22H16FN3O2 |
| Molecular Weight | 373.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxamide.
1-(4-Fluorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 946352-89-2) is a high-purity analytical reference standard with the molecular formula C22H16FN3O2 and a molecular weight of 373.38 g/mol.
Structurally, 1-(4-Fluorobenzyl)-2-oxo-N-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxamide (C22H16FN3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 373.38 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H16FN3O2 |
| Molecular Weight | 373.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorobenzyl Standards
- 4-Fluorobenzyl (1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)carbamate (CAS 866143-87-5)
- N-(5-((2-Fluorobenzyl)thio)-1,3,4-thiadiazol-2-yl)-3-phenylpropanamide (CAS 535945-91-6)
- (E)-2-(4-((4-fluorobenzyl)oxy)styryl)-5-nitrobenzonitrile (CAS 307952-88-1)
- 3-(3-((2-Fluorobenzyl)oxy)phenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 1234692-27-3)
- 3-[(4-Fluorobenzyl)oxy]-N-[(E)-(4-fluorophenyl)methylidene]-2-thiophenecarbohydrazide (CAS 478246-48-9)
- (E)-3-((4-fluorobenzyl)oxy)-N'-((3-methylthiophen-2-yl)methylene)thiophene-2-carbohydrazide (CAS 478246-49-0)
- 2-((4-Fluorobenzyl)thio)-5-phenyl-1-(p-tolyl)-1H-imidazole (CAS 1206989-86-7)
- 2-((4-Fluorobenzyl)thio)-5-phenyl-1-(o-tolyl)-1H-imidazole (CAS 1207043-50-2)
Recommended Standards
- 4-chloro-2-methyl-6-nitrophenol (CAS 1760-71-0)
- 2-[4-(4-Nitrophenyl)piperazino]ethyl 4-fluorobenzenecarboxylate (CAS 338748-59-7)
- 2-Amino-5-(4-fluorophenyl)-5-[(3,4,5-trimethoxyphenyl)methyl]-4,5-dihydro-1H-imidazol-4-one (CAS 1354932-17-4)
- 2-Acetamido-N1-(4-fluorobenzyl)-N3-(4-methoxyphenyl)malonamide (CAS 551921-07-4)
- 5-(2-fluoroethoxy)-1H-indole (CAS 1240407-43-5)
- Benzenesulfonamide, 3-amino-N-(1,1-dimethylethyl)-5-fluoro- (CAS 1339536-41-2)
- 3-Methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-amine (CAS 1006448-59-4)
- 2,3,5,6-Tetramethoxybenzaldehyde (CAS 34602-86-3)
- methyl 3-[4-(chloromethyl)-1,3-thiazol-2-yl]benzoate (CAS 479578-92-2)
- Dexibuprofen Isopropyl Ester (CAS 1114975-39-1)
- 2-Bromo-4-chloro-1-(4-fluorophenyl)butan-1-one (CAS 51037-74-2)
- (3AS,4R,6R,7aR)-2-benzyl-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole (CAS 78922-83-5)
- 3-(Trifluoromethyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 24848-34-8)
- Neuroendocrine Regulatory Peptide-1 (human) (H-6622.1000) (CAS 954420-50-9)
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