2-Amino-3-(difluoromethoxy)pyridine CAS 947249-14-1
| CAS No. | 947249-14-1 |
| Molecular Formula | C6H6F2N2O |
| Molecular Weight | 160.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C6H6F2N2O, 2-Amino-3-(difluoromethoxy)pyridine contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 160.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Amino-3-(difluoromethoxy)pyridine (CAS 947249-14-1), molecular formula C6H6F2N2O and molecular weight 160.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6F2N2O |
| Molecular Weight | 160.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-2-(difluoromethoxy)pyridine (CAS 1214344-58-7)
- 3-Amino-1-(difluoromethyl)pyridin-2(1H)-one (CAS 1263181-53-8)
- 3-Amino-6-(difluoromethyl)pyridin-2(1H)-one (CAS 1443292-51-0)
- 4-Amino-1-(difluoromethyl)pyridin-2(1H)-one (CAS 1708079-34-8)
- 5-Amino-1-(difluoromethyl)pyridin-2(1H)-one (CAS 1779123-38-4)
- 6-Amino-5-(difluoromethyl)pyridin-3-ol (CAS 1805028-99-2)
- 4-Amino-5-(difluoromethyl)pyridin-2-ol (CAS 1805301-53-4)
- 4-Amino-6-(difluoromethyl)pyridin-2-ol (CAS 1806762-30-0)
Recommended Standards
- 2,6-Difluoro-4-methoxyphenol (CAS 886498-93-7)
- 2-Methyl-4-oxopentanedioic acid (CAS 55601-64-4)
- 2,6-Difluoro-4-hydroxybenzyl Alcohol (CAS 438049-36-6)
- 3-(3,3-difluorocyclobutyl)prop-2-ynoic acid (CAS 2613384-93-1)
- Valdecoxib Impurity 1 (CAS 1391052-01-9)
- 4-[(4-Bromophenyl)sulfanyl]-6-{[(4-chlorophenyl)sulfanyl]methyl}-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine (CAS 341965-51-3)
- 1-Cyclopropyl-2-methyl-3-(pyridin-4-yl)propane-1,3-dione (CAS 1482168-54-6)
- (S)-2-(2-((dimethylamino)methyl)pyrrolidin-1-yl)acetic acid (CAS 1353994-95-2)
- (R)-(-)-Camptothecin (CAS 110351-92-3)
- (R)-N-((S)-1,3-Dihydrospiro[indene-2,4'-piperidin]-1-yl)-2-methylpropane-2-sulfinamide (CAS 2245085-41-8)
- Losartan Impurity 42 (CAS 2901098-91-5)
- N-(4-Bromophenyl)-4-fluorobenzenesulfonamide (CAS 727-32-2)
- 8-Chloro-2-(2-methoxyphenyl)quinoline-4-carboxylic acid (CAS 862649-89-6)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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