Perphenazine Impurity 2 CAS 95296-27-8
| CAS No. | 95296-27-8 |
| Molecular Formula | C12H9N3O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Perphenazine Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Perphenazine Impurity 2 (CAS 95296-27-8) is a certified pharmaceutical impurity reference standard with the molecular formula C12H9N3OHCl and a molecular weight of 247.68 g/mol.
Based on its molecular formula C12H9N3OHCl, Perphenazine Impurity 2 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 247.68 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H9N3O HCl |
| Molecular Weight | 247.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Perphenazine Standards
- Perphenazine EP Impurity A (CAS 10078-25-8)
- Perphenazine-D8 (as Dihydrochloride) (CAS 1189961-11-2)
- Perphenazine Impurity 6 (CAS 1254074-25-3)
- Perphenazine-d4 (CAS 155593-75-2)
- Perphenazine DiHCl (Fluphenazine Dihydrochloride EP Impurity E DiHCl) (CAS 2015-28-3)
- Perphenazine-D8 dihydrochloride (CAS 2070015-23-3)
- Perphenazine Impurity 5 (CAS 2760728-14-9)
- Perphenazine Impurity C27 (CAS 2765-59-5)
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