5-Chloro-7-fluoroindoline CAS 954264-12-1
| CAS No. | 954264-12-1 |
| Molecular Formula | C8H7ClFN |
| Molecular Weight | 171.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-7-fluoroindoline.
5-Chloro-7-fluoroindoline (CAS 954264-12-1) is a high-purity analytical reference standard with the molecular formula C8H7ClFN and a molecular weight of 171.60 g/mol.
Structurally, 5-Chloro-7-fluoroindoline (C8H7ClFN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 171.60 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-7-fluoroindoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClFN |
| Molecular Weight | 171.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-6-fluoroindoline (CAS 1003005-39-7)
- 5-Chloro-4-fluoroindoline (CAS 1222804-82-1)
- 7-Chloro-4-fluoroindoline (CAS 1700248-22-1)
- 2-Chloro-5-(1-fluorocyclopropyl)pyridine (CAS 2839739-50-1)
- 4-Chloro-5-fluoroindoline (CAS 903551-32-6)
- 5-Chloro-6-fluoroindoline (CAS 935272-19-8)
- 6-CHLORO-5-FLUORO-2,3-DIHYDRO-1H-INDOLE (CAS 205584-67-4)
- 7-Chloro-5-fluoroindoline (CAS 953903-54-3)
Recommended Standards
- Selexipag Impurity 5 (CAS 202658-88-6)
- 2-Chlorothiazolo[4,5-b]pyrazine (CAS 1190927-25-3)
- 5-Allyl-2-chloro-3-fluoropyridine (CAS 1353529-74-4)
- 2-Chloro-3-isothiocyanatopyrazine (CAS 127648-53-7)
- 4-Fluoropyridine-3-sulfonyl chloride (CAS 1060809-59-7)
- 2-(1H-Indol-4-yl)ethanamine (CAS 16176-73-1)
- 1-Chloro-4-methylanthracene-9,10-dione (CAS 7477-59-0)
- 5-Fluoro-2-nitrophenyl trifluoromethanesulphonate (CAS 722536-31-4)
- 5,6-difluoro-3,4-dihydroquinazolin-4-one (CAS 933823-89-3)
- 5-((4-(tert-Butyl)-2-chlorophenoxy)methyl)-1,3,4-oxadiazol-2-amine (CAS 1706452-11-0)
- 2,3-Diphenylbutane-2,3-diol (CAS 1636-34-6)
- 2-BROMO-2-METHYLPROPAN-1-AMINE HBR (CAS 36565-68-1)
- Janagliflozin impurity 5 (CAS CATO-C4X-30325)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
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