1-Chloro-2-(1,1,2,2-tetrafluoroethoxy)benzene CAS 957372-65-5

Description

Compared with other compounds in its class, the molecular weight of 228.57 g/mol gives 1-Chloro-2-(1,1,2,2-tetrafluoroethoxy)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Chloro-2-(1,1,2,2-tetrafluoroethoxy)benzene (CAS 957372-65-5), molecular formula C8H5ClF4O and molecular weight 228.57 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-Chloro-2-(1,1,2,2-tetrafluoroethoxy)benzene (C8H5ClF4O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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