Prednisolone Acetate EP Impurity E CAS 4380-55-6
| CAS No. | 4380-55-6 |
| Molecular Formula | C23H28O5 |
| Molecular Weight | 384.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Prednisolone Acetate EP Impurity E (CAS 4380-55-6), a pharmacopoeial impurity reference standard (molecular formula C23H28O5, MW 384.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H28O5, Prednisolone Acetate EP Impurity E contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 384.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H28O5 |
| Molecular Weight | 384.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Prednisolone Standards
- Prednisolone Impurity 5 (CAS 2141-22-2)
- Prednisolone impurity 58 (CAS 19357-45-0)
- 6α-Methyl Prednisolone-d3 (CAS CATO-C4X-173725)
- Prednisolone EP Impurity D (CAS 16355-29-6)
- Prednisolone EP Impurity E (CAS 95815-58-0)
- Prednisolone Impurity 19 (CAS 61549-70-0)
- Prednisolone impurity 59 (CAS CATO-C4X-173759)
- Prednisolone Impurity 32 (CAS CATO-C4X-173732)
Recommended Standards
- Eplerenone Impurity 29 (CAS CATO-C4X-163029)
- Peramivir Impurity 84 (CAS CATO-C4X-183384)
- Eplerenone Impurity 28 (CAS CATO-C4X-163028)
- Vincamine EP Impurity A (CAS 57430-34-9)
- Pramipexole impurity 77 (CAS CATO-C4X-110777)
- Pomalidomide Impurity 13 (CAS 636-65-7)
- Phenytoin EP Impurity F (CAS 51169-17-6)
- 4-(((1-Methyl-1h-pyrazol-5-yl)methyl)amino)butan-2-ol (CAS 1343936-52-6)
- 3-(2-Hydroxy-4-methylquinolin-3-yl)propanoic acid (CAS 36796-90-4)
- (1-(tert-butoxycarbonyl)-5-(cyclohexylamino)-1H-indol-2-yl)boronic acid (CAS 1021342-94-8)
- (2R,3S,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-(2-chloroethoxy)tetrahydro-2H-pyran-3,4-diyl diacetate (CAS 887641-02-3)
- 3-Methoxy-1-phenyl-1H-indole-2-carboxylic acid (CAS 85793-71-1)
- (S)-2-Methyl-2H-pyran-4(3H)-one (CAS 190912-15-3)
- (Cys2)-Neuropeptide Y-8-aminooctanoyl-(D-Cys27)-Neuropeptide Y (25-32) (H-3298.0500) (CAS 128806-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com