Edaravone Impurity 26 CAS 96-96-8
| CAS No. | 96-96-8 |
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Edaravone Impurity 26 (CAS 96-96-8, C7H8N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Edaravone Impurity 26 (C7H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 168.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Edaravone Standards
Recommended Standards
- 4-Methanehydrazonoylbenzene-1,2,3-triol (CAS 1865681-56-6)
- Esomeprazole Impurity 28 (CAS 577-72-0)
- ethyl 3-forMyl-4,5-dihydro-1H-pyrazole-5-carboxylate (CAS 93290-12-1)
- Esomeprazole Impurity 44 (CAS 16133-49-6)
- Troxerutin Impurity 9 (CAS CATO-C4X-28009)
- Abemaciclib Impurity 130 (CAS CATO-C4X-2937130)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
- N-(4-(N-(1-Methyl-2-oxoindolin-5-yl)sulfamoyl)phenyl)propionamide (CAS 921862-18-2)
- Venetoclax Impurity 31 (CAS CATO-C4X-249531)
- 2-(Difluoromethyl)-3,4-dihydroxypyridine-6-carboxaldehyde (CAS 1805325-55-6)
- Cyclobuta[b]quinoxaline-1,2(3H,8H)-dione (CAS 20420-52-4)
- Edoxaban Impurity 31 (CAS 259809-24-0)
- 2H-Oxazolo[5,4-g]indole (CAS 117025-06-6)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com