Esomeprazole Impurity 28 CAS 577-72-0
| CAS No. | 577-72-0 |
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 168.15 g/mol gives Esomeprazole Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Esomeprazole Impurity 28 (CAS 577-72-0), a pharmacopoeial impurity reference standard (molecular formula C7H8N2O3, MW 168.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Esomeprazole Impurity 28 (C7H8N2O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 168.15 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Esomeprazole Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O3 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
Related Esomeprazole Standards
- Esomeprazole Impurity 44 (CAS 16133-49-6)
- Esomeprazole Impurity 66 (CAS 14248-66-9)
- Esomeprazole Impurity 105 (CAS 86604-78-6)
- Esomeprazole Impurity 115 (CAS 1424857-83-9)
- Esomeprazole Impurity 40 (CAS 86604-80-0)
- Esomeprazole Impurity 39 (CAS 92806-98-9)
- Esomeprazole Impurity 97 (CAS 142885-88-9)
- Esomeprazole Impurity 106 (CAS 110464-72-7)
Recommended Standards
- Edaravone Impurity 26 (CAS 96-96-8)
- 4-Methanehydrazonoylbenzene-1,2,3-triol (CAS 1865681-56-6)
- ethyl 3-forMyl-4,5-dihydro-1H-pyrazole-5-carboxylate (CAS 93290-12-1)
- Lansoprazole Impurity 24 (CAS 168167-49-5)
- Brexpiprazole Impurity 165 (CAS CATO-C4X-1131165)
- Haloperidol Impurity 22 (CAS 660844-75-7)
- Everolimus Impurity 12 (CAS CATO-C4X-112212)
- 2-(Dimethylamino)acetyl Chloride Hydrochloride (CAS 60853-81-8)
- 2-Propenoic acid, 2-methyl-,1,1'-(1,4-phenylene) ester 3049-31-8 CTK4G5320 (CAS 3049-31-8)
- 1-(3,4-Dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-2-fluoroethan-1-amine (CAS 929972-19-0)
- 2-Amino-N-methyl-N-((1-methylpyrrolidin-3-yl)methyl)acetamide (CAS 1342476-43-0)
- 7-Chloro-5-methylthieno[3,2-b]pyridine (CAS 1211582-14-7)
- 3-(Piperidin-4-ylmethyl)cyclobutan-1-ol (CAS 2168994-07-6)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com