Olmesartan Impurity 59 CAS 971-85-7
| CAS No. | 971-85-7 |
| Molecular Formula | C21H18O2 |
| Molecular Weight | 302.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Olmesartan Impurity 59 (CAS 971-85-7, C21H18O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H18O2, Olmesartan Impurity 59 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 302.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18O2 |
| Molecular Weight | 302.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Olmesartan Standards
- Olmesartan Impurity 45 (CAS 866721-92-8)
- Olmesartan impurity 103 (CAS 93641-16-8)
- Olmesartan Impurity 14 (CAS 144978-05-2)
- Olmesartan Impurity 29 (CAS 76-83-5)
- Olmesartan Impurity 76 (CAS 161952-66-5)
- Olmesartan impurity 88 (CAS CATO-C4X-109788)
- Olmesartan Impurity 57 (CAS CATO-C4X-109757)
- Olmesartan Impurity 32 (CAS 1092980-85-2)
Recommended Standards
- 2,2'-(Piperazine-1,4-diyl)diethanesulfonic Acid (CAS 5625-37-6)
- Vildagliptin Impurity 113 (CAS 3099756-00-7)
- 203258-44-0 tert-butyl N-[N'-(2-aminoethyl)-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamimidoyl]carbamate (CAS 203258-44-0)
- Vildagliptin Impurity 65 (CAS CATO-C4X-110065)
- Empagliflozin impurity 263 (CAS CATO-C4X-1065263)
- Clindamycin Impurity 20 (CAS CATO-C4X-1341120)
- Salbutamol Impurity 138 Trifluoroacetic Acid (CAS CATO-C4X-1176138)
- 2-Cyclopropylbenzo[d]oxazole (CAS 63359-58-0)
- 2-Allylphenylboronic Acid (CAS 372193-58-3)
- Tegoprazan impurity 37 (CAS CATO-C4X-229737)
- N-(3-chloro-4-fluorophenyl)-2-((furan-2-ylmethyl)amino)-2-thioxoacetamide (CAS 329078-84-4)
- 4-(2-Aminoacetamido)butanoic acid (CAS 32595-49-6)
- 4-(Aminomethyl)-3-ethyl-4-methylhexan-3-ol (CAS 1519582-25-2)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
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