Nabumetone Impurity 27 CAS 98386-82-4
| CAS No. | 98386-82-4 |
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Nabumetone Impurity 27 (CAS 98386-82-4, C15H14O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Nabumetone Impurity 27 (C15H14O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Nabumetone Impurity 27 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
Related Nabumetone Standards
- Nabumetone Impurity 5 (CAS 73356-31-7)
- Nabumetone Impurity 12 (CAS 2740579-68-2)
- Nabumetone Impurity 23 (CAS 56290-45-0)
- Nabumetone impurity 31 (CAS CATO-C4X-284831)
- Nabumetone Impurity 8 (CAS 5672-98-0)
- Nabumetone Impurity 25 (CAS CATO-C4X-284825)
- Nabumetone Impurity 14 (CAS CATO-C4X-284814)
- Nabumetone Impurity 28 (CAS 98386-83-5)
Recommended Standards
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