Nabumetone Impurity 8 CAS 5672-98-0
| CAS No. | 5672-98-0 |
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Nabumetone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Nabumetone Impurity 8 (CAS 5672-98-0) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14O3 and a molecular weight of 242.27 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system, Nabumetone Impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Nabumetone Standards
- Nabumetone Impurity 5 (CAS 73356-31-7)
- Nabumetone Impurity 12 (CAS 2740579-68-2)
- Nabumetone Impurity 23 (CAS 56290-45-0)
- Nabumetone Impurity 27 (CAS 98386-82-4)
- Nabumetone impurity 31 (CAS CATO-C4X-284831)
- Nabumetone Impurity 25 (CAS CATO-C4X-284825)
- Nabumetone Impurity 14 (CAS CATO-C4X-284814)
- Nabumetone Impurity 28 (CAS 98386-83-5)
Recommended Standards
- Nemonoxacin Impurity 119 (CAS CATO-C4X-3128119)
- (2-Hydroxy-4-methoxyphenyl)(4-methylphenyl)methanone (CAS 1641-17-4)
- Fenoprofen (CAS 29679-58-1)
- Phenethyl Salicylate (CAS 87-22-9)
- Rosuvastatin EP Impurity G (CAS 1242184-42-4)
- Nifuroxazide EP Impurity D (CAS 736-53-8)
- Clodronate Disodium EP Impurity D (CAS 87591-00-2)
- (S)-(1-nitrosopyrrolidin-2-yl)methanol (CAS CATO-C4X-219638)
- 2-(2,3-Dichlorophenyl)-2-(piperidin-1-yl)acetic acid (CAS 1218310-40-7)
- 3-Chloro-1-propyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile (CAS 2512765-32-9)
- 7,8-Dichloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (CAS 300675-28-9)
- (R)-(-)-Bromo Dragonfly-d6 Hydrochloride (CAS 1246816-43-2)
- 4-methylthiolan-3-amine (CAS 115660-79-2)
- Tau Peptide (298-312) trifluoroacetate salt (CAS 330456-47-8)
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