Nabumetone Impurity 12 CAS 2740579-68-2
| CAS No. | 2740579-68-2 |
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Nabumetone Impurity 12 (CAS 2740579-68-2), a pharmacopoeial impurity reference standard (molecular formula C15H14O3, MW 242.27 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Nabumetone Impurity 12 (C15H14O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nabumetone Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14O3 |
| Molecular Weight | 242.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
Related Nabumetone Standards
- Nabumetone Impurity 5 (CAS 73356-31-7)
- Nabumetone Impurity 23 (CAS 56290-45-0)
- Nabumetone Impurity 27 (CAS 98386-82-4)
- Nabumetone impurity 31 (CAS CATO-C4X-284831)
- Nabumetone Impurity 8 (CAS 5672-98-0)
- Nabumetone Impurity 25 (CAS CATO-C4X-284825)
- Nabumetone Impurity 14 (CAS CATO-C4X-284814)
- Nabumetone Impurity 28 (CAS 98386-83-5)
Recommended Standards
- Nifekalant impurity 7 (CAS CATO-C4X-27977)
- Ozefloxacin Impurity 20 (CAS CATO-C4X-279620)
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- Semaglutide impurity 331 (CAS CATO-C4X-2226231)
- Fenofibrate Impurity 21 (CAS CATO-C4X-164321)
- Alectinib Impurity 11 (CAS 1256698-41-5)
- Pirfenidone Impurity 29 (CAS 53427-93-3)
- 1-(tert-Butyldimethylsilyl)-5-fluoropyrrolo[2,3-b]pyridine-4-carboxylic acid (CAS 2055119-32-7)
- 2,2'-Diiodo-4,4',6,6'-tetramethyl-1,1'-biphenyl (CAS 503178-35-6)
- Atrasentan Impurity 77 (CAS 1058551-16-8)
- 3-Bromo-8-chloro-2-(4-methoxyphenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 866137-67-9)
- Aminoxyacetamide-PEG3-azide (CAS 1379761-16-6)
- tert-Butyl 3-((2-hydroxyethyl)amino)azetidine-1-carboxylate (CAS 178311-50-7)
- Akt/SKG Substrate Peptide (CAS 276680-69-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com