Azithromycin-13C-d3 CAS CATO-C4X-100337
| CAS No. | CATO-C4X-100337 |
| Molecular Formula | C37[13C]H69D3N2O12 |
| Molecular Weight | 753.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Azithromycin-13C-d3.
Azithromycin-13C-d3 (CAS CATO-C4X-100337) is a high-purity analytical reference standard with the molecular formula C37[13C]H69D3N2O12 and a molecular weight of 753.00 g/mol.
The molecular framework of Azithromycin-13C-d3 (C37[13C]H69D3N2O12) is characterized by deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C37[13C]H69D3N2O12 |
| Molecular Weight | 753.00 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Azithromycin Standards
- Azithromycin-13CD3 (CAS CATO-CCAD301299)
- Azithromycin-d3 (CAS 163921-65-1)
- Azithromycin-d5 (major) (CAS CATO-CCAD301941)
- Azithromycin Impurity 49 (CAS CATO-C4X-100349)
- Azithromycin (CAS 83905-01-5)
- Azithromycin EP Impurity M (CAS 765927-71-7)
- Azithromycin Impurity 40 (CAS 76820-32-1)
- Azithromycin impurity 55 (CAS 944124-75-8)
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