Azithromycin-d3 CAS 163921-65-1
| CAS No. | 163921-65-1 |
| Molecular Formula | - |
| Molecular Weight | 752.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Azithromycin-d3.
CATO supplies Azithromycin-d3 (CAS 163921-65-1), a certified reference material (molecular formula C38H69D3N2O12, MW 752.00 g/mol) for analytical method development and quality control.
Structurally, Azithromycin-d3 (C38H69D3N2O12) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 752.00 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C38H69D3N2O12 |
| Molecular Weight | 752.00 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 2 |
Related Azithromycin Standards
- Azithromycin-13C-d3 (CAS CATO-C4X-100337)
- Azithromycin-13CD3 (CAS CATO-CCAD301299)
- Azithromycin-d5 (major) (CAS CATO-CCAD301941)
- Azithromycin Impurity 49 (CAS CATO-C4X-100349)
- Azithromycin (CAS 83905-01-5)
- Azithromycin EP Impurity M (CAS 765927-71-7)
- Azithromycin Impurity 40 (CAS 76820-32-1)
- Azithromycin impurity 55 (CAS 944124-75-8)
Recommended Standards
- 1-(4-Methoxyphenyl)-5-phenylpentane-1,3,5-trione (CAS 1678-17-7)
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- Elobixibat Impurity 4 (CAS CATO-C4X-28384)
- 2,3-Bis(dodecyloxy)propyl (6-methyl-3-oxo-3H-phenoxazin-7-yl) glutarate (CAS 195833-46-6)
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- Ethyl 7-bromo-2,4-dichloroquinoline-3-carboxylate (CAS 2758820-34-5)
- 1-Methyl-4-nitro-1h-pyrrole-2-carboxamide (CAS 13138-77-7)
- Tosylproline (CAS 370883-85-5)
- N-(4-Bromobenzyl)-4-methoxybenzamide (CAS 281668-93-7)
- 4-((5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)but-2-yn-1-ol (CAS 727386-40-5)
- Cyclopropanecarboxylic acid, 1-amino-2-ethenyl-, (1R,2S)- (CAS 159700-58-0)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
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