Apremilast Impurity 70 CAS CATO-C4X-100970
| CAS No. | CATO-C4X-100970 |
| Molecular Formula | C16H10N2O6 |
| Molecular Weight | 326.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Apremilast Impurity 70 (C16H10N2O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Apremilast Impurity 70 (CAS CATO-C4X-100970) is a certified pharmaceutical impurity reference standard with the molecular formula C16H10N2O6 and a molecular weight of 326.26 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Apremilast Impurity 70 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10N2O6 |
| Molecular Weight | 326.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Apremilast Standards
- Apremilast Impurity 51 (CAS 2097600-16-1)
- Apremilast impurity 64 (CAS CATO-C4X-100964)
- Apremilast impurity 94 (CAS CATO-C4X-100994)
- Apremilast impurity 95 (CAS CATO-C4X-100995)
- Apremilast Impurity 122 (CAS CATO-C4X-1009122)
- Apremilast Impurity 35 (CAS CATO-C4X-100935)
- Apremilast Impurity 77 (CAS CATO-C4X-100977)
- Apremilast Impurity 123 (CAS CATO-C4X-1009123)
Recommended Standards
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- Sofosbuvir impound 124 (CAS 2875066-41-2)
- Ethacridine Lactate Impurity 34 (CAS CATO-C4X-260934)
- Azilsartan Impurity 115 (CAS CATO-C4X-1096115)
- Deoxycholic acid Impurity 4 (CAS CATO-C4X-33594)
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