Baclofen Impurity 48 CAS CATO-C4X-101248
| CAS No. | CATO-C4X-101248 |
| Molecular Formula | C15H14ClNO4 |
| Molecular Weight | 307.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Baclofen Impurity 48 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Baclofen Impurity 48 (CAS CATO-C4X-101248, C15H14ClNO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Baclofen Impurity 48 (C15H14ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Baclofen Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14ClNO4 |
| Molecular Weight | 307.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen Impurity 49 (CAS CATO-C4X-101249)
- Baclofen Impurity 36 (CAS CATO-C4X-101236)
- Baclofen Impurity 50 (CAS CATO-C4X-101250)
- Baclofen impurity 43 (CAS CATO-C4X-101243)
- Baclofen impurity 44 (CAS CATO-C4X-101244)
- Baclofen Impurity 58 (CAS CATO-C4X-101258)
- Baclofen Impurity 65 (CAS CATO-C4X-101265)
- Baclofen impurity 9 (CAS 101104-10-3)
Recommended Standards
- 3-(4-chlorophenoxy)-6-phenyl-4-pyridazinecarbonitrile 338751-61-4 KS-000038TF (CAS 338751-61-4)
- N1-(5-Chloro-2-cyanophenyl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 899744-13-9)
- N1-(5-Chloropyridin-2-yl)-N2-(2-(2-methyl-1H-imidazol-1-yl)ethyl)oxalamide (CAS 1208546-56-8)
- N-(5-Chloro-2,4-dimethoxyphenyl)-3-(furan-2-yl)acrylamide (CAS 853349-21-0)
- Timolol EP Impurity I (CAS CATO-C4X-149611)
- Piperacillin Impurity 82 (CAS CATO-C4X-173282)
- Cefoxitin Impurity 45 (CAS CATO-C4X-157845)
- 4-Bromo-N,N-dimethylnaphthalene-1-sulfonamide (CAS 898645-97-1)
- (R)-3-((tert-Butoxycarbonyl)amino)pentanoic acid (CAS 183990-60-5)
- Methyl 2-(2,3-dichlorophenyl)propanoate (CAS 1249476-63-8)
- Ethyl 6-hydroxypyridine-2-carboxylate (CAS 53389-00-7)
- 3-(3-(Amino(p-tolyl)methyl)-1H-1,2,4-triazol-5-yl)phenol (CAS 1708371-14-5)
- Tert-butyl 4-(2-nitrobenzamido)piperidine-1-carboxylate (CAS 1043962-60-2)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com