Baclofen Impurity 54 CAS CATO-C4X-101254
| CAS No. | CATO-C4X-101254 |
| Molecular Formula | C10H10ClNO3 |
| Molecular Weight | 227.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Baclofen Impurity 54 (CAS CATO-C4X-101254, C10H10ClNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Baclofen Impurity 54 (C10H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 227.64 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H10ClNO3 |
| Molecular Weight | 227.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Baclofen Standards
- Baclofen Impurity 75 (CAS CATO-C4X-101275)
- Baclofen Impurity 46 (CAS CATO-C4X-101246)
- Baclofen Impurity 53 (CAS CATO-C4X-101253)
- Baclofen Impurity 1 (CAS 53911-68-5)
- Baclofen Impurity 28 (CAS 70410-34-3)
- Baclofen impurity 23 (CAS 84803-46-3)
- Baclofen-d4 (Major) (CAS 70155-52-1)
- Baclofen-d4 (CAS 1189938-30-4)
Recommended Standards
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- N-1,3-Benzodioxol-5-yl-2-chloropropanamide (CAS 90476-87-2)
- Palbociclib Impurity 134 (CAS CATO-C4X-1125134)
- Venetoclax Impurity 18 (CAS CATO-C4X-249518)
- Benzoic Acid impurity 6 (CAS 2497-91-8)
- 2-N-Cyclopentylpyridine-2,5-diamine (CAS 52025-59-9)
- 2-(pyrrolidin-1-yl)ethanethioamide (CAS 760898-91-7)
- 1-Acetyl-5-bromo-6-chloro-1H-indol-3-yl acetate (CAS 108847-96-7)
- 1,3,3-Trimethyl-1-(pyrrolidin-3-yl)urea (CAS 1284978-60-4)
- 2-(3-methyl-1H-1,2,4-triazol-5-yl)morpholine (CAS 1249510-08-4)
- Parahydroxybenzoic acid-α-<SUP>13</SUP>C (CAS 146672-02-8)
- Neuropeptide EI (human, mouse, rat) (CAS 125934-45-4)
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