Lifitegrast Impurity 9 CAS 1289646-72-5
| CAS No. | 1289646-72-5 |
| Molecular Formula | C28H23Cl2N |
| Molecular Weight | 444.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lifitegrast Impurity 9 is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Lifitegrast Impurity 9 (CAS 1289646-72-5), a pharmacopoeial impurity reference standard (molecular formula C28H23Cl2N, MW 444.39 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C28H23Cl2N, Lifitegrast Impurity 9 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 444.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lifitegrast Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H23Cl2N |
| Molecular Weight | 444.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 45 (CAS CATO-C4X-240945)
- Lifitegrast Impurity 13 (CAS CATO-C4X-240913)
- Lifitegrast Impurity 135 (CAS CATO-C4X-2409135)
- Lifitegrast Impurity 166 (CAS CATO-C4X-2409166)
- Lifitegrast Impurity 172 (CAS CATO-C4X-2409172)
- Lifitegrast Impurity 154 (CAS CATO-C4X-2409154)
- Lifitegrast Impurity 155 (CAS CATO-C4X-2409155)
- Lifitegrast Impurity 100 (CAS CATO-C4X-2409100)
Recommended Standards
- Z-Gly-Gly-Gly-ONP (CAS 19811-64-4)
- Idebenone Impurity 8 (CAS CATO-C4X-30168)
- Rothindin (CAS 63347-43-3)
- 2-(4-Chlorophenyl)-5-((4-chlorophenyl)thio)-4-(4-methoxyphenyl)thiazole (CAS 865658-09-9)
- Posaconazole Impurity 49 (CAS 1902954-05-5)
- Dabigatran Impurity 77 (CAS 5436-02-2)
- Lafutidine impurity 16 (CAS 129622-98-6)
- 1-(Methylsulfonyl)-4-methylpiperazine (CAS 59039-17-7)
- N-(5-Chloro-2-methoxyphenyl)-1-(3,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 890885-18-4)
- Methyl 5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine-3-carboxylate (CAS 1710194-45-8)
- 1-[(3-Methylphenyl)methyl]-1,4-diazepane (CAS 926249-17-4)
- Sulbenicillin Impurity 3 (CAS CATO-C4X-23243)
- 2-propylcyclopentan-1-one (CAS 1193-70-0)
- Peptide 432 (CAS CATO-CPTD788432)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com