Vonoprazan Impurity 236 Fumarate Salt CAS CATO-C4X-1020236
| CAS No. | CATO-C4X-1020236 |
| Molecular Formula | C32H25F2N5O4S2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vonoprazan Impurity 236 Fumarate Salt.
As a process- or degradation-related impurity, Vonoprazan Impurity 236 Fumarate Salt (CAS CATO-C4X-1020236, C32H25F2N5O4S2C4H4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Vonoprazan Impurity 236 Fumarate Salt (C32H25F2N5O4S2C4H4O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vonoprazan Impurity 236 Fumarate Salt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C32H25F2N5O4S2 C4H4O4 |
| Molecular Weight | 761.77 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 298 (CAS 103860-56-6)
- Vonoprazan Impurity 82 (CAS 106058-86-0)
- Vonoprazan Fumarate Impurity 71 (CAS 1060802-18-7)
- Vonoprazan Impurity 129 (CAS 109-00-2)
- Vonoprazan Impurity 188 (CAS 111480-82-1)
- Vonoprazan Impurity 195 (CAS 1126403-28-8)
- Vonoprazan Impurity 10 (CAS 122453-85-4)
- Vonoprazan Impurity 89 (CAS 1224739-02-9)
Recommended Standards
- Resmetirom impurity 136 (CAS CATO-C4X-2912136)
- Rimegepant Impurity 113 (CAS 1452167-10-0)
- Risedronate 2.5-Hydrate EP Impurity E (CAS 75755-10-1)
- 3-(3-Acetylbenzenesulfonamido)propanoic acid (CAS 568554-51-8)
- Benzyl 2-amino-3-phenylpropanoate hydrochloride (CAS 58780-66-8)
- 4-(3-(2-Bromophenyl)-5-mercapto-4h-1,2,4-triazol-4-yl)-1,5-dimethyl-2-phenyl-1,2-dihydro-3h-pyrazol-3-one (CAS 732287-94-4)
- Pyronaridine Impurity 14 (CAS 1596337-67-5)
- 4-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]benzoic acid (CAS 101187-49-9)
- 2-[3-(3-Chloro-phenyl)-propyl]-6-methoxy-benzoic acid methyl ester (CAS 1171923-22-0)
- Neuropeptide FF (CAS 99566-27-5)
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