Carfilzomib Impurity D3 CAS CATO-C4X-102258
| CAS No. | CATO-C4X-102258 |
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Carfilzomib Impurity D3 (CAS CATO-C4X-102258) is a certified pharmaceutical impurity reference standard with the molecular formula C40H59N5O8 and a molecular weight of 737.93 g/mol.
Based on its molecular formula C40H59N5O8, Carfilzomib Impurity D3 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 737.93 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Carfilzomib Standards
- Carfilzomib Impurity 41 (CAS CATO-C4X-102241)
- Carfilzomib Impurity 42 (CAS CATO-C4X-102242)
- Carfilzomib Impurity 48 (CAS 1541172-75-1)
- Carfilzomib Impurity 50 (CAS CATO-C4X-102250)
- Carfilzomib Impurity D4 (CAS CATO-C4X-102259)
- Carfilzomib Impurity 63 (CAS CATO-C4X-102263)
- Carfilzomib Impurity 67 (CAS CATO-C4X-102267)
- Carfilzomib Impurity 68 (CAS CATO-C4X-102268)
Recommended Standards
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- Carfilzomib Impurity 70 (CAS CATO-C4X-102270)
- Furosemide Impurity 50 (CAS CATO-C4X-140250)
- Fasudil Impurity 7 (CAS 85-48-3)
- Esomeprazole Impurity 87 (CAS CATO-C4X-111287)
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