Carfilzomib Impurity 70 CAS CATO-C4X-102270
| CAS No. | CATO-C4X-102270 |
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Carfilzomib Impurity 70 (CAS CATO-C4X-102270), a pharmacopoeial impurity reference standard (molecular formula C40H59N5O8, MW 737.93 g/mol) used for the identification and quantification of trace impurities in APIs.
Carfilzomib Impurity 70 (C40H59N5O8) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Carfilzomib Standards
- Carfilzomib Impurity 41 (CAS CATO-C4X-102241)
- Carfilzomib Impurity 42 (CAS CATO-C4X-102242)
- Carfilzomib Impurity 48 (CAS 1541172-75-1)
- Carfilzomib Impurity 50 (CAS CATO-C4X-102250)
- Carfilzomib Impurity D3 (CAS CATO-C4X-102258)
- Carfilzomib Impurity D4 (CAS CATO-C4X-102259)
- Carfilzomib Impurity 63 (CAS CATO-C4X-102263)
- Carfilzomib Impurity 67 (CAS CATO-C4X-102267)
Recommended Standards
- Carfilzomib Impurity 69 (CAS CATO-C4X-102269)
- Carfilzomib Impurity 71 (CAS CATO-C4X-102271)
- Carfilzomib Impurity 68 (CAS CATO-C4X-102268)
- Carfilzomib Impurity 72 (CAS CATO-C4X-102272)
- Celecoxib Impurity 22 (CAS 163266-02-2)
- Salbutamol Impurity 210 (CAS CATO-C4X-1176210)
- N-Nitroso Metronidazole Impurity 32 (CAS CATO-C4X-140532)
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- 4-(trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine (CAS 1190309-89-7)
- Zirconium tetrakis(2,2,6,6-tetramethyl-3,5-pimelate) (CAS 18865-74-2)
- 2-(4-Fluorophenyl)-N-((2-methoxyadamantan-2-yl)methyl)acetamide (CAS 1797025-61-6)
- 3,3-Difluoro-2,2-dimethylbutanoic acid (CAS 130021-54-4)
- rel-(4S,5R)-4-Hydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one (CAS 73209-20-8)
- Semaglutide (CAS 910463-68-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com