Carfilzomib Impurity D4 CAS CATO-C4X-102259
| CAS No. | CATO-C4X-102259 |
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, Carfilzomib Impurity D4 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 737.93 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Carfilzomib Impurity D4 (CAS CATO-C4X-102259, C40H59N5O8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Carfilzomib Impurity D4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C40H59N5O8 |
| Molecular Weight | 737.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Carfilzomib Standards
- Carfilzomib Impurity 41 (CAS CATO-C4X-102241)
- Carfilzomib Impurity 42 (CAS CATO-C4X-102242)
- Carfilzomib Impurity 48 (CAS 1541172-75-1)
- Carfilzomib Impurity 50 (CAS CATO-C4X-102250)
- Carfilzomib Impurity D3 (CAS CATO-C4X-102258)
- Carfilzomib Impurity 63 (CAS CATO-C4X-102263)
- Carfilzomib Impurity 67 (CAS CATO-C4X-102267)
- Carfilzomib Impurity 68 (CAS CATO-C4X-102268)
Recommended Standards
- Carfilzomib Impurity 69 (CAS CATO-C4X-102269)
- Carfilzomib Impurity 70 (CAS CATO-C4X-102270)
- 2-(dimethylamino)pyrimidin-4-ol (CAS 1635-28-5)
- Carfilzomib Impurity 71 (CAS CATO-C4X-102271)
- Tropicamide Impurity 21 (CAS 96392-48-2)
- Mosapride Impurity 27 (CAS 112914-13-3)
- Relugolix Impurity 107 (CAS CATO-C4X-2429107)
- Olmesartan Impurity 21 (CAS 172875-98-8)
- Malic Acid Impurity 12 (CAS CATO-C4X-250912)
- Ciprocinonide (CAS 58524-83-7)
- 2-Chlorobenzylzinc chloride 0.5 M in Tetrahydrofuran (CAS 312624-11-6)
- 2,3-Dibromo-5-(difluoromethyl)-4-methoxypyridine (CAS 1805958-89-7)
- 5-Bromo-2,3-difluoro-4-ethoxyphenol (CAS 2271443-08-2)
- Serpent Peptide (CAS 823202-99-9)
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