rac-Paroxetine HCl Hemihydrate Impurity C CAS CATO-C4X-103542
| CAS No. | CATO-C4X-103542 |
| Molecular Formula | C21H25NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, rac-Paroxetine HCl Hemihydrate Impurity C (CAS CATO-C4X-103542, C21H25NO4HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
rac-Paroxetine HCl Hemihydrate Impurity C (C21H25NO4HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), rac-Paroxetine HCl Hemihydrate Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H25NO4 HCl |
| Molecular Weight | 391.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related rac Standards
- Paroxetine Impurity 62 (CAS 100332-12-5)
- Paroxetine Impurity 43 (CAS 100332-20-5)
- Paroxetine EP Impurity G HCl (CAS 1012886-75-7)
- Paroxetine Impurity 24 (CAS 105812-81-5)
- Paroxetine EP impurity C (CAS 105813-14-7)
- Paroxetine HCl EP Impurity C (CAS 105813-14-7(free base))
- Paroxetine EP Impurity F HCl (CAS 105813-39-6)
- Paroxetine Impurity 47 (CAS 105813-40-9)
Recommended Standards
- Tetrabenazine Impurity 46 (CAS CATO-C4X-274846)
- Pethidine EP Impurity B (CAS 28289-54-5)
- Levetiracetam Impurity 26 (CAS 20496-01-9)
- 2-Methoxypyrimidine-4,6-diamine (CAS 856595-47-6)
- 8-Iodoquinolin-6-ol (CAS 857758-15-7)
- 6-(4-Ethylphenyl)-3-(ethylthio)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 894047-92-8)
- tert-Butyl 3-((6-chloropyridazin-3-yl)amino)piperidine-1-carboxylate (CAS 939986-11-5)
- tert-Butyl (1-carbamothioylcyclopropyl)carbamate (CAS 1159733-28-4)
- N-(4-Acetyl-3-methoxyphenyl)acetamide (CAS 51410-08-3)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
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