Donepezil impurity 68 CAS CATO-C4X-103968
| CAS No. | CATO-C4X-103968 |
| Molecular Formula | 2*C24H27NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Donepezil impurity 68 (CAS CATO-C4X-103968) is a certified pharmaceutical impurity reference standard with the molecular formula C24H27NO3 and a molecular weight of 377.48 g/mol.
Donepezil impurity 68 (C24H27NO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Donepezil impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C24H27NO3 |
| Molecular Weight | 377.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 15 (CAS 1023500-88-0)
- Donepezil Impurity 44 (CAS 1026443-48-0)
- Donepezil Impurity 46 (CAS 1034439-43-4)
- Donepezil-d5 (CAS 1128086-25-8)
- Donepezil Impurity 55 (CAS 1189443-74-0 (free base))
- Donepezil Related Compound A HCl (CAS 120011-69-0)
- Donepezil Hydrochloride (CAS 120011-70-3)
- Donepezil Impurity 25 (CAS 120012-04-6)
Recommended Standards
- Cefpodoxime Proxetil EP Impurity G (CAS 947692-15-1)
- Progesterone Impurity 97 (CAS CATO-C4X-150297)
- Resmetirom Impurity 3 (CAS 6629-04-5)
- Relebactam Impurity 62 (CAS 1174020-24-6)
- Tert-butyl (S)-3,3-difluoro-4-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2382120-13-8)
- 2-(1-oxo-1,2-dihydroisoquinolin-2-yl)propanoic acid (CAS 344461-41-2)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen [2,3'-bithiophen]-5-ylboronate (CAS 1402166-53-3)
- 4,5,6,7-Tetrahydrofuro[3,2-c]pyridine-2-carbaldehyde (CAS 1707605-76-2)
- (S)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl acrylate (CAS 127604-93-7)
- Semaglutide Impurity 158 (x TFA Salt) (CAS CATO-C4X-2226158)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com