Donepezil Impurity 74 CAS CATO-C4X-103974
| CAS No. | CATO-C4X-103974 |
| Molecular Formula | C25H31NO3 |
| Molecular Weight | 393.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C25H31NO3, Donepezil Impurity 74 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 393.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Donepezil Impurity 74 (CAS CATO-C4X-103974, C25H31NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H31NO3 |
| Molecular Weight | 393.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 51 (CAS CATO-C4X-103951)
- Donepezil Impurity 53 (CAS 149874-81-7)
- Donepezil Impurity 15 (CAS 1023500-88-0)
- Donepezil Impurity 31 (CAS 2097683-67-3)
- Donepezil EP impurity C (CAS 2452407-76-8)
- Donepezil Impurity 7 (CAS 120013-84-5)
- Donepezil Impurity 40 (CAS 923571-16-8)
- Donepezil D7 (CAS 1215071-00-3)
Recommended Standards
- Nalmefene Impurity 21 (CAS CATO-C4X-126821)
- Nalmefene Impurity 6 (CAS CATO-C4X-12686)
- N-(4-(N-(2-(Pyrrolidin-1-yl)-2-(thiophen-3-yl)ethyl)sulfamoyl)phenyl)acetamide (CAS 946356-93-0)
- Amiodarone EP Impurity A (CAS 23551-25-9)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Ibuprofen Impurity 91 (CAS CATO-C4X-108291)
- Phentolamine Impurity 8 (CAS 2767988-83-8)
- MTX-211 (CAS 1952236-05-3)
- Cefaclor Impurity 56 (CAS CATO-C4X-127056)
- (Z)-4-amino-N'-(3-cyano-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide (CAS 914474-51-4)
- Hexahydro-1H-thieno[3,4-c]pyrrole hydrochloride (CAS 1378710-42-9)
- (S)-2-(2-(1H-Indol-3-yl)acetamido)-3-phenylpropanoic acid (CAS 57105-50-7)
- Favipiravir Impurity 8 (CAS 356783-29-4)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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