Regorafenib Impurity 9 CAS CATO-C4X-10479
| CAS No. | CATO-C4X-10479 |
| Molecular Formula | C27H24FN7O4 |
| Molecular Weight | 529.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Regorafenib Impurity 9.
Regorafenib Impurity 9 (CAS CATO-C4X-10479) is a certified pharmaceutical impurity reference standard with the molecular formula C27H24FN7O4 and a molecular weight of 529.52 g/mol.
Based on its molecular formula C27H24FN7O4, Regorafenib Impurity 9 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 529.52 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Regorafenib Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H24FN7O4 |
| Molecular Weight | 529.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Regorafenib Standards
- Regorafenib EP Impurity D (CAS 2438857-80-6)
- Regorafenib Impurity 84 (CAS CATO-C4X-104784)
- Regorafenib-13C-d3 N-Oxide (CAS 835621-11-9 (Unlabeled))
- Regorafenib Impurity 13 (CAS 835621-11-9)
- Regorafenib Impurity 16 (CAS 1343498-71-4)
- Regorafenib Impurity 75 (CAS CATO-C4X-104775)
- Regorafenib Impurity 12 (CAS CATO-C4X-104712)
- Regorafenib-13C-D3 (CAS 2126178-55-8)
Recommended Standards
- N-((5-((2-((4-Fluorophenyl)amino)-2-oxoethyl)thio)-4-(3-(trifluoromethyl)phenyl)-4H-1,2,4-triazol-3-yl)methyl)benzamide (CAS 393839-83-3)
- Cefoperazone EP Impurity A (CAS 73240-08-1)
- 4-((2-Tetradecanoylhydrazineylidene)methyl)phenyl 4-bromobenzoate (CAS 765274-17-7)
- Nilotinib Hydrochloride Monohydrate EP Impurity H (CAS 641571-15-5)
- Chlorthalidone impurity 16 (CAS CATO-C4X-158516)
- Terbutaline impurity 116 (CAS CATO-C4X-1183116)
- Lornoxicam Impurity 8 (CAS 13120-39-3)
- 1,2-Benzenediamine, 4-methyl-n2-(2-methylpropyl)- (CAS 640768-14-5)
- Fmoc-1-aminomethyl-cyclohexane carboxylic acid (CAS 220145-22-2)
- 2-(3-(1H-pyrrol-1-yl)thiophen-2-yl)-5-(2-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine (CAS 478039-23-5)
- (S)-2,2'-Dimethyl-1,1'-binaphthyl (CAS 32587-64-7)
- 1-[(2-Methoxyphenyl)methyl]cyclobutan-1-amine hydrochloride (CAS 1439902-23-4)
- 6-(2-Aminophenyl)picolinic acid (CAS 885276-97-1)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com