Chlorthalidone impurity 16 CAS CATO-C4X-158516
| CAS No. | CATO-C4X-158516 |
| Molecular Formula | C15H12ClNO4S |
| Molecular Weight | 337.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Chlorthalidone impurity 16 (CAS CATO-C4X-158516) is a certified pharmaceutical impurity reference standard with the molecular formula C15H12ClNO4S and a molecular weight of 337.78 g/mol.
Chlorthalidone impurity 16 (C15H12ClNO4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C15H12ClNO4S |
| Molecular Weight | 337.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorthalidone Standards
- Chlorthalidone Impurity 7 (CAS 345930-31-6)
- Chlorthalidone (CAS 77-36-1)
- Chlorthalidone impurity 19 (CAS CATO-C4X-158519)
- Chlorthalidone-d4 (CAS 1794941-44-8)
- Chlorthalidone impurity 17 (CAS CATO-C4X-158517)
- Chlorthalidone Impuruty 8 (CAS 82875-49-8)
- Chlorthalidone impurity 20 (CAS 96512-76-4)
- Chlorthalidone impurity 18 (CAS 87177-16-0)
Recommended Standards
- Tizanidine Impurity 62 (CAS CATO-C4X-144562)
- Dotinurad Impurity 30 (CAS CATO-C4X-249430)
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- 4-(4-Chlorobenzoyl)-8-methyl-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1009354-95-3)
- Istradefylline Impurity 19 (CAS 155272-03-0)
- Argatroban Impurity 13 (CAS 94975-84-5)
- Repotrectinib Impurity 1 (CAS 1802221-21-1)
- 2-Amino-4-chloro-n-ethylbenzamide (CAS 2953-62-0)
- 8-Chloro-2,3,4,9-tetrahydro-1h-carbazol-1-amine (CAS 1042626-75-4)
- 3-Chloropropylmalonate diethyl ester (CAS 18719-43-2)
- 1-Ethyl-N-isobutyl-4-nitro-1H-pyrazol-3-amine (CAS 1429418-05-2)
- (2-Chloro-3-cyano-5-cyclopropylphenyl)boronic acid (CAS 2225172-77-8)
- Ethyl 2-(piperidin-4-ylmethyl)cyclopropane-1-carboxylate (CAS 2580238-65-7)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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