Ceritinib Impurity 2 CAS CATO-C4X-10482
| CAS No. | CATO-C4X-10482 |
| Molecular Formula | C21H30ClN5O |
| Molecular Weight | 403.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ceritinib Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ceritinib Impurity 2 (CAS CATO-C4X-10482) is a certified pharmaceutical impurity reference standard with the molecular formula C21H30ClN5O and a molecular weight of 403.95 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Ceritinib Impurity 2 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 403.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H30ClN5O |
| Molecular Weight | 403.95 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Ceritinib Standards
- Ceritinib Impurity 86 (CAS /)
- Ceritinib Impurity 10 (CAS CATO-C4X-1048910)
- Ceritinib Impurity 55 (CAS CATO-C4X-104855)
- Ceritinib Impurity 39 (CAS CATO-C4X-104839)
- Ceritinib Impurity 43 (CAS CATO-C4X-104843)
- Ceritinib Impurity 45 (CAS CATO-C4X-104845)
- Ceritinib Impurity 48 (CAS CATO-C4X-104848)
- Ceritinib Impurity 26 (CAS CATO-C4X-104826)
Recommended Standards
- N-(3-chlorophenyl)-2-((5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)propanamide (CAS 332161-81-6)
- Tris(2,2,3,3-tetrafluoropropyl) borate (CAS 2317-76-2)
- 2-[(4-Chlorophenyl)sulfanyl]-4,6-dimethyl-3-(4-methylbenzenesulfonyl)pyridine (CAS 478245-42-0)
- 4-Chloro Perphenazine (CAS 875256-24-9)
- Resmetirom impurity 54 (CAS 62918-73-4)
- Hydroxychloroquine Impurity N54 (CAS 5448-52-2)
- Posaconazole Impurity 203 (CAS CATO-C4X-1208203)
- 1-Chloro-n-(furan-3-ylmethyl)-n-methylmethanesulfonamide (CAS 1342360-16-0)
- 1-(4-Fluoroindolin-1-yl)ethanone (CAS 860024-83-5)
- 436092-90-9 2-[5-(4-Aminophenyl)-2H-tetrazol-2-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide DTXSID20357664 (CAS 436092-90-9)
- Benzothiophene-6-sulfonyl Chloride (CAS 685129-19-5)
- 2-(1-Methyl-1H-pyrazol-4-yl)-2-(methylamino)ethan-1-ol (CAS 1184061-03-7)
- 3-Amino-N-(4-fluorophenyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 496801-80-0)
- D-Leu14-Tirzepatide (CAS CATO-CPTD788920)
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