Ceritinib Impurity 23 CAS CATO-C4X-104823
| CAS No. | CATO-C4X-104823 |
| Molecular Formula | C13H13Cl2N3S |
| Molecular Weight | 314.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ceritinib Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ceritinib Impurity 23 (CAS CATO-C4X-104823) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13Cl2N3S and a molecular weight of 314.23 g/mol.
The molecular framework of Ceritinib Impurity 23 (C13H13Cl2N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C13H13Cl2N3S |
| Molecular Weight | 314.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 16 (CAS CATO-C4X-104816)
- Ceritinib Impurity 22 (CAS CATO-C4X-104822)
- Ceritinib Impurity 24 (CAS CATO-C4X-104824)
- Ceritinib Impurity 18 (CAS CATO-C4X-1048918)
- Ceritinib Impurity 82 (CAS CATO-C4X-104882)
- Ceritinib Impurity 17 (CAS CATO-C4X-104817)
- Ceritinib Impurity 1 (CAS CATO-C4X-10481)
- Ceritinib Impurity 83 (CAS CATO-C4X-104883)
Recommended Standards
- 2-Bromo-1-(3,4-dihydro-2h-1,4-benzothiazin-4-yl)-3-methylbutan-1-one (CAS 1097794-82-5)
- N-(3,5-Bis(trifluoromethyl)phenyl)(propylamino)formamide (CAS 23751-81-7)
- N'-(6-Bromo-1,3-benzothiazol-2-yl)-N,N-dimethylpropane-1,3-diamine (CAS 1105195-16-1)
- N-(2,4-dichlorophenyl)-1-(2-(ethylthio)-1-methyl-1H-imidazol-5-yl)methanimine (CAS 320423-10-7)
- Thiamphenicol Impurity 1 (CAS 56724-21-1)
- Tranexamic Acid Impurity 6 (CAS CATO-C4X-17716)
- Penfluridol Impurity 3 (CAS CATO-C4X-35383)
- Methyl 3-(thiophene-2-carboxamido)thiophene-2-carboxylate (CAS 545351-07-3)
- (2-Nitrobenzyl)triphenylphosphonium bromide (CAS 23308-83-0)
- 2-Butoxy-1,1-Difluorocyclopropane (CAS 133744-89-5)
- Pseudoisoeugenyl 2-methylbutyrate (CAS 58989-20-1)
- 1-Benzyl-2-methyl-1H-indole-3-carbonitrile (CAS 639499-85-7)
- [1-(3-methylphenyl)cyclopentyl]methanamine (CAS 1098349-30-4)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
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